Safety Profile of Valtoco® (diazepam nasal spray) in Patients With Epilepsy: Final Results From a Phase 3, Open-Label, 12-Month Repeat Dose Safety Study

被引：0

作者：

Wheless, James ^{[1
]}

Sperling, Michael ^{[2
]}

Liow, Kore ^{[3
]}

Segal, Eric ^{[4
,5
]}

Miller, Ian ^{[6
]}

Hogan, R. Edward ^{[7
]}

Tarquinio, Daniel ^{[8
]}

Desai, Jay ^{[9
]}

Dlugos, Dennis ^{[10
]}

Biton, Victor ^{[11
]}

Cascino, Gregory ^{[12
]}

Carrazana, Enrique ^{[13
]}

Rabinowicz, Adrian L. ^{[13
]}

机构：

[1] UTHSC Pesdiat Neurol, Memphis, TN USA

[2] Thomas Jefferson Univ Hosp, Philadelphia, PA 19107 USA

[3] Hawaii Pacific Neurosci, Honolulu, HI USA

[4] Hackensack Univ, Med Ctr, Hackensack, NJ USA

[5] Northeast Reg Epilepsy Grp, Hackensack, NJ USA

[6] Nicklaus Childrens Hosp, Coral Terrace, FL USA

[7] Washington Univ, St Louis, MO 14263 USA

[8] Ctr Rare Neurol Dis, Norcross, GA USA

[9] Childrens Hosp Los Angeles, Los Angeles, CA 90027 USA

[10] Childrens Hosp Philadelphia, Philadelphia, PA 19104 USA

[11] Clin Trials Inc, Res Triangle Pk, NC USA

[12] Mayo Clin, Rochester, MN USA

[13] Neurelis Inc, San Diego, CA USA

来源：

NEUROLOGY | 2021年 / 96卷 / 15期

关键词：

D O I：

暂无

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

1753

引用

页数：5

共 50 条

[1] Safety of diazepam nasal spray (Valtoco®) in patients with epilepsy: Final results from a phase 3, open-label, 12-month, repeat-dose safety study
Wheless, James
Sperling, Michael
Liow, Kore
Segal, Eric
Hogan, Robert
Tarquinio, Daniel
Mauney, Weldon
Desai, Jay
Dlugos, Dennis
Biton, Victor
Cascino, Gregory
Carrazana, Enrique
Rabinowicz, Adrian
[J]. EPILEPSIA, 2021, 62 : 146 - 147
[2] Safety of Valtoco™ (NRL-1; Diazepam Nasal Spray) in Children and Adolescents with Epilepsy: Interim Subgroup Results from a Phase 3, Open-Label, 12-Month Repeat Dose Study
Segal, E.
Tarquinio, D.
Miller, I
Dlugos, D.
Wheless, J.
Carrazana, E.
[J]. ANNALS OF NEUROLOGY, 2019, 86 : S71 - S71
[3] A 12-month, open-label, repeat-dose safety study of Valtoco™ (NRL-1, diazepam nasal spray) in patients with epilepsy: Interim report
Sperling, Michael
Hogan, Robert
Biton, Victor
Tarquinio, Daniel
Carrazana, Enrique
[J]. NEUROLOGY, 2019, 92 (15)
[4] Effectiveness and Safety of Valtoco® (NRL-1; diazepam nasal spray) in Patients With Epilepsy and a History of Seasonal Allergies: Interim Results From a Phase 3, Open-Label, 12-Month Repeat Dose Study
Vazquez, Blanca
Sperling, Michael R.
Wheless, James W.
Liow, Kore
Segal, Eric B.
Miller, Ian
Hogan, R. Edward
Tarquinio, Daniel
Mauney, Weldon
Desai, Jay
Dlugos, Dennis
Ayala, Ricardo
Biton, Victor
Cascino, Gregory D.
Carrazana, Enrique
Rabinowicz, Adrian L.
[J]. NEUROLOGY, 2020, 94 (15)
[5] Safety of Valtoco® (Diazepam Nasal Spray) in Children and Adolescents With Epilepsy: Final Subgroup Results From a Phase 3, Long-Term Open-Label, Repeat-Dose Safety Study
Tarquinio, D.
Dlugos, D.
Wheless, J.
Desai, J.
Boro, A.
Carrazana, E.
Rabinowicz, A.
[J]. ANNALS OF NEUROLOGY, 2021, 90 : S128 - S128
[6] Time to Second Doses in Children and Adolescents With Epilepsy Treated With Valtoco® (Diazepam Nasal Spray): Final Subgroup Results From a Phase 3, Open-Label, Repeat-Dose Safety Study
Tarquinio, D.
Dlugos, D.
Wheless, J.
Desai, J.
Boro, A.
Rabinowicz, A.
Carrazana, E.
[J]. ANNALS OF NEUROLOGY, 2021, 90 : S124 - S124
[7] Final results from a Phase 3, long-term, open-label, repeat-dose safety study of diazepam nasal spray for seizure clusters in patients with epilepsy
Wheless, James W.
Miller, Ian
Hogan, R. Edward
Dlugos, Dennis
Biton, Victor
Cascino, Gregory D.
Sperling, Michael R.
Liow, Kore
Vazquez, Blanca
Segal, Eric B.
Tarquinio, Daniel
Mauney, Weldon
Desai, Jay
Rabinowicz, Adrian L.
Carrazana, Enrique
[J]. EPILEPSIA, 2021, 62 (10) : 2485 - 2495
[8] Lack of observed tolerance to diazepam nasal spray (Valtoco®) after long-term rescue therapy in patients with epilepsy: Interim results from a phase 3, open-label, repeat-dose safety study
Cascino, Gregory D.
Tarquinio, Daniel
Wheless, James W.
Hogan, R. Edward
Sperling, Michael R.
Liow, Kore
Desai, Jay
Davis, Charles
Rabinowicz, Adrian L.
Carrazana, Enrique
[J]. EPILEPSY & BEHAVIOR, 2021, 120
[9] Time to Second Doses in Emergency Seizure Patients Treated With Valtoco® (diazepam nasal spray) Across 24 Hours: Subgroup Results From a Completed Phase 3, Open-label, Repeat Dose Safety Study
Wheless, James
Sperling, Michael
Liow, Kore
Segal, Eric
Miller, Ian
Hogan, R. Edward
Tarquinio, Daniel
Desai, Jay
Dlugos, Dennis
Biton, Victor
Cascino, Gregory
Rabinowicz, Adrian L.
Carrazana, Enrique
[J]. NEUROLOGY, 2021, 96 (15)
[10] Consistent safety and tolerability of Valtoco(R) (diazepam nasal spray) in relationship to usage frequency in patients with seizure clusters: Interim results from a phase 3, long-term, open-label, repeat-dose safety study
Miller, Ian
Wheless, James W.
Hogan, Robert E.
Dlugos, Dennis
Biton, Victor
Cascino, Gregory D.
Sperling, Michael R.
Liow, Kore
Vazquez, Blanca
Segal, Eric B.
Tarquinio, Daniel
Mauney, Weldon
Desai, Jay
Rabinowicz, Adrian L.
Carrazana, Enrique
[J]. EPILEPSIA OPEN, 2021, 6 (03) : 504 - 512

← 1 2 3 4 5 →