Characteristics of Fluent and Non-Fluent Primary Progressive Aphasia

被引：5
|
作者：
Lange, Inga [1 ]
Grande, Marion [1 ]
Willmes, Klaus [2 ]
Kastrau, Frank [3 ]
Fimm, Bruno [2 ]
Heim, Stefan [1 ,4 ,5 ]
Huber, Walter [1 ]
机构：
[1] Rhein Westfal TH Aachen, Fak Med, Sekt Klin Kognit Forsch, Aachen, Germany
[2] Rhein Westfal TH Aachen, Fak Med, Lehr & Forsch Gebiet Neuropsychol, Aachen, Germany
[3] Rhein Westfal TH Aachen, Fak Med, Neurol Klin, Aachen, Germany
[4] Rhein Westfal TH Aachen, Fak Med, Klin Psychiat Psychotherapie & Psychosomat, Sekt Strukturell Funkt Brain Mapping, Aachen, Germany
[5] Forschungszentrum Julich, Inst Neurowissensch & Med INM 1, D-52425 Julich, Germany
来源：
ZEITSCHRIFT FUR NEUROPSYCHOLOGIE | 2012年 / 23卷 / 01期
关键词：
primary progressive aphasia; frontotemporal lobar degeneration; language decline; dementia; SEMANTIC DEMENTIA; 3; VARIANTS; FEATURES; DISEASE;
D O I：
10.1024/1016-264X/a000057
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Primary progressive aphasia (PPA) is a dementia with primarily deterioration of language abilities. The aim of the current study was to describe patterns of language decline using the Aachen Aphasia Test (AAT), with a view to differentiate the characteristics of fluent and non-fluent PPA. 20 patients were assessed in a retrospective study, 14 of them repeatedly. Patients with fluent PPA were significantly more impaired in the AAT-spontaneous speech rating scale semantic structure and in the subtest confrontation naming than patients with non-fluent PPA. In advanced stages of the disease, no intergroup differences were present any more. Mild and fast progression of language decline could be documented. A change of fluent to non-fluent PPA could be observed in two patients.
引用
收藏
页码：7 / 18
页数：12
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