Synthesis and Biological Evaluation of Some Novel Phenyl Thiazole Derivatives as Possible Antimicrobial Agents

被引：0

作者：

Kittur, B. S. ^{[1
]}

Sastry, B. S.

Prasad, Y. Rajendra ^{[2
]}

Pattan, S. R. ^{[3
]}

Srinivas, Y. ^{[4
]}

机构：

[1] HSK Coll Pharm, Dept Pharmaceut Chem & Pharmacognosy, Bagalkot 587101, Karnataka, India

[2] Andhra Univ Visakhapatnam, Univ Coll Pharmaceut Sci, Dept Pharmaceut Chem, Visakhapatnam, Andhra Pradesh, India

[3] Pravara Rural Coll Pharm Loni, Dept Pharmaceut Chem, Bombay, Maharashtra, India

[4] HSK Coll Pharm, Dept Pharmacognosy, Bagalkot 587101, Karnataka, India

来源：

INDIAN JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH | 2011年 / 45卷 / 02期

关键词：

Phenyl thiazole; Antitubercular; Antibacterial and Antifungal; TUBERCULOSIS;

D O I：

暂无

中图分类号：

G40 [教育学];

学科分类号：

040101 ; 120403 ;

摘要：

A new series of phenyl thiazole derivatives has been synthesized by condensing ortho diketone, substituted aldehydes and aromatic amines. The structures of these compounds were established by spectral data. All the synthesized compounds have been screened for their antitubercular activity against Mycobacterium tuberculosis H-37 Rv strain and antimicrobial activity against E. coli, S. aureus, A. niger and C. albicans. Most of the compounds have shown significant antitubercular, antibacterial and antifungal activities when compared with the standard drugs.

引用

页码：157 / 163

页数：7

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