Serum cystatin C is associated with other cardiovascular risk markers and cardiovascular disease in elderly men

被引：14
|
作者：
Larsson, Anders [1 ]
Helmersson, Johanna [2 ]
Hansson, Lars-Olof [1 ]
Basu, Samar [2 ]
机构：
[1] Univ Uppsala Hosp, Dept Med Sci, Sect Clin Chem, S-75185 Uppsala, Sweden
[2] Univ Uppsala Hosp, Dept Publ Hlth & Caring Sci, Sect Clin Nutr Res, Uppsala, Sweden
来源：
INTERNATIONAL JOURNAL OF CARDIOLOGY | 2008年 / 125卷 / 02期
关键词：
cardiovascular disease; cystatin C; diabetes mellitus; glomerular filtration rate; kidney; human;
D O I：
10.1016/j.ijcard.2007.07.113
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Renal dysfunction is associated with increased cardiovascular morbidity and mortality. The aim of this cross-sectional study was to investigate the relationship between the glomerular filtration marker cystatin C and other cardiovascular risk markers and morbidity in elderly males. Cystatin C was measured in a group of 77-year-old males (n = 792) and compared cystatin C with other known risk markers for cardiovascular disease. Cystatin C values were significantly increased in individuals with diabetes (p = 0.05) and cardiovascular diseases (p<0.0001). There were significant correlations between cystatin C values and body mass index, HbA1c, insulin, triglycerides and hsCRP. (C) 2007 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码：263 / 264
页数：2
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