Antibody Teamwork against Ebola Virus Disease

被引：0
|
作者：
Zehner, Matthias [1 ,2 ]
Klein, Florian [1 ,2 ,3 ,4 ]
机构：
[1] Univ Cologne, Inst Virol, Fac Med, Expt Immunol Lab, D-50931 Cologne, Germany
[2] Univ Cologne, Univ Hosp Cologne, D-50931 Cologne, Germany
[3] Univ Cologne, Ctr Mol Med Cologne, D-50931 Cologne, Germany
[4] Ctr Infect Res, Partner Site Bonn Cologne, D-50931 Cologne, Germany
来源：
IMMUNITY | 2020年 / 52卷 / 02期
基金：
欧洲研究理事会;
关键词：
D O I：
10.1016/j.immuni.2020.01.016
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Antibodies are key components to prevent and treat Ebola virus disease (EVD). In this issue of Immunity, Gilchuk et al. decipher the underlying mechanism of two antibodies that cooperatively target Ebolaviruses. The study provides insight into an antibody combination that potentiates antiviral activity and is able to prevent EVD in nonhuman primates.
引用
收藏
页码：217 / 219
页数：4
相关论文
共 50 条
  • [1] Antibody therapeutics for Ebola virus disease
    Zeitlin, Larry
    Whaley, Kevin J.
    Olinger, Gene G.
    Jacobs, Michael
    Gopal, Robin
    Qiu, Xiangguo
    Kobinger, Gary P.
    [J]. CURRENT OPINION IN VIROLOGY, 2016, 17 : 45 - 49
  • [2] Monoclonal Antibody Therapy for Ebola Virus Disease
    Levine, Myron M.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2019, 381 (24): : 2365 - 2366
  • [3] Antibody-mediated protection against Ebola virus
    Saphire, Erica Ollmann
    Schendel, Sharon L.
    Gunn, Bronwyn M.
    Milligan, Jacob C.
    Alter, Galit
    [J]. NATURE IMMUNOLOGY, 2018, 19 (11) : 1169 - 1178
  • [4] Antibody-mediated protection against Ebola virus
    Erica Ollmann Saphire
    Sharon L. Schendel
    Bronwyn M. Gunn
    Jacob C. Milligan
    Galit Alter
    [J]. Nature Immunology, 2018, 19 : 1169 - 1178
  • [5] The road to effective and accessible antibody therapies against Ebola virus
    Fausther-Bovendo, Hugues
    Kobinger, Gary
    [J]. CURRENT OPINION IN VIROLOGY, 2022, 54
  • [6] Nurses Leading the Fight Against Ebola Virus Disease
    Sagar, Priscilla L.
    [J]. JOURNAL OF TRANSCULTURAL NURSING, 2015, 26 (03) : 322 - 326
  • [7] Characterization of a Novel Neutralizing Monoclonal Antibody Against Ebola Virus GP
    Reynard, Olivier
    Volchkov, Viktor E.
    [J]. JOURNAL OF INFECTIOUS DISEASES, 2015, 212 : S372 - S378
  • [8] DEVELOPMENT OF AN ELISA TEST FOR THE DETECTION OF ANTIBODY AGAINST MARBURG AND EBOLA VIRUS
    SLENCZKA, W
    HOFFMANN, C
    [J]. MEDICAL MICROBIOLOGY AND IMMUNOLOGY, 1981, 169 (02) : 157 - 157
  • [9] Monoclonal antibody prophylaxis protects against lethal Ebola virus infection
    James, Rebekah
    Stonier, Spencer W.
    Bakken, Russell
    Bornholdt, Zachary A.
    Dye, John M.
    [J]. JOURNAL OF IMMUNOLOGY, 2018, 200 (01):
  • [10] Identification and Characterization of a Novel Single Domain Antibody Against Ebola Virus
    Wang, Rui
    Zhang, Haiwei
    Peng, Cheng
    Shi, Jian
    Zhang, Huajun
    Gong, Rui
    [J]. VIROLOGICA SINICA, 2021, 36 (06) : 1600 - 1610
12345