Finding the Right Match Fast

被引：3
|
作者：
Nandakumar, Divya [1 ]
Patel, Smita S. [1 ]
机构：
[1] Rutgers Robert Wood Johnson Med Sch, Dept Biochem & Mol Biol, Princeton, NJ 08544 USA
来源：
CELL | 2015年 / 160卷 / 05期
关键词：
HOMOLOGOUS RECOMBINATION; TIME;
D O I：
10.1016/j.cell.2015.02.007
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
DNA recombinases face the daunting task of locating and pairing up specific sequences among millions of base pairs in a genome, all within about an hour. Qi et al. show that recombinases solve this problem by searching in 8-nt microhomology units, reducing the search space and accelerating the homology search.
引用
收藏
页码：809 / 811
页数：3
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