Left atrial appendage occlusion for stroke prevention in patients with atrial fibrillation

被引：8

作者：

Bajwa, Rizma Jalees ^{[1
]}

Kovell, Lara ^{[1
]}

Resar, Jon R. ^{[1
]}

Arbab-Zadeh, Armin ^{[1
]}

Mandal, Kaushik ^{[2
]}

Calkins, Hugh ^{[1
]}

Berger, Ronald D. ^{[1
]}

机构：

[1] Johns Hopkins Univ, Sch Med, Div Cardiol, 1800 Orleans St, Baltimore, MD 21287 USA

[2] Johns Hopkins Univ, Sch Med, Div Cardiac Surg, Baltimore, MD USA

来源：

CLINICAL CARDIOLOGY | 2017年 / 40卷 / 10期

关键词：

Atrial Fibrillation; Left Atrial Appendage Occlusion; Stroke Prevention; SHORT-TERM; CLOSURE; WARFARIN; DEVICE; RISK; ANTICOAGULATION; FEASIBILITY; EXPERIENCE; THERAPY; REDUCE;

D O I：

10.1002/clc.22764

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Atrial fibrillation (AF) is a commonly sustained atrial arrhythmia with associated morbidity and mortality. AF is associated with increased risk of thromboembolism and stroke, requiring use of anticoagulation. Anticoagulation decreases the risk of stroke but is associated with a higher risk of bleeding, necessitating discontinuation in some patients. The left atrial appendage is the likely source of thrombus in the majority of patients with AF. This has led to the development of left atrial appendage occlusion as a means to reduce stroke risk in patients who have a contraindication to long-term anticoagulation. Multiple implantable devices have surfaced in the last few years, with some promising prospects. The main purpose of this review is to highlight the indications and use of these devices for left atrial appendage occlusion.

引用

页码：825 / 831

页数：7

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