A study on biomarkers of sepsis and potential role of procalcitonin and ferritin marker in diagnosis, prognosis and treatment

被引:6
|
作者
Samuel, Marcella Sherin [1 ]
Latha, Ragunathan [1 ]
Kavitha, Kannaiyan [1 ]
Sivasubramanian, Vithiavathi [2 ]
机构
[1] Vinayaka Missions Res Fdn Deemed Univ, Aarupadai Veedu Med Coll & Hosp, Dept Microbiol, Pondicherry, India
[2] Vinayaka Missions Res Fdn Deemed Univ, Aarupadai Veedu Med Coll & Hosp, Dept Gen Med, Pondicherry, India
关键词
CRP; ferritin; inflammatory biomarkers; procalcitonin; sepsis; TIME;
D O I
10.4103/jfmpc.jfmpc_1920_21
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Objectives: To evaluate the potential value of serum procalcitonin and serum ferritin levels in patients with clinically suspected and proven sepsis and their comparison with established inflammatory markers like C-reactive protein (CRP) and total leukocyte count. Materials and Methods: A total of GO clinically suspected cases of sepsis were included in this study and each patient was investigated for serum S. ferritin, procalcitonin, and CRP and blood cultures using the BacT/Alert system. Results: Serum procalcitonin at a cut-off value of >2 ng/ml is a valuable biomarker for early diagnosis in sepsis patients due to bacterial infection and has a greater predictive value than serum ferritin, CRP, or any other biomarkers.
引用
收藏
页码:2608 / 2612
页数:5
相关论文
共 50 条
  • [1] Biomarkers of sepsis and their potential value in diagnosis, prognosis and treatment
    Sandquist, Mary
    Wong, Hector R.
    [J]. EXPERT REVIEW OF CLINICAL IMMUNOLOGY, 2014, 10 (10) : 1349 - 1356
  • [2] Procalcitonin and the role of biomarkers in the diagnosis and management of sepsis
    Riedel, Stefan
    [J]. DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 2012, 73 (03) : 221 - 227
  • [3] Procalcitonin: Potential Role in Diagnosis and Management of Sepsis
    Rowland, Tim
    Hilliard, Heather
    Barlow, Gavin
    [J]. ADVANCES IN CLINICAL CHEMISTRY, VOL 68, 2015, 68 : 71 - 86
  • [4] PROCALCITONIN AS A MARKER FOR EARLY DIAGNOSIS OF SEPSIS
    Raoofi, Rahim
    Salmani, Zahra
    Moradi, Fatemh
    Sotoodeh, Abdolrerza
    Sobhanian, Saeed
    [J]. AMERICAN JOURNAL OF INFECTIOUS DISEASES, 2014, 10 (01) : 15 - 20
  • [5] Procalcitonin: A Reliable Marker for the Diagnosis of Neonatal Sepsis
    Adib, Minoo
    Bakhshiani, Zahra
    Navaei, Fakhri
    Fosoul, Fereshteh Saheb
    Fouladi, Salomeh
    Kazemzadeh, Hamidreza
    [J]. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 2012, 15 (02) : 777 - 782
  • [6] Procalcitonin's role in the sepsis cascade. Is procalcitonin a sepsis marker or mediator?
    Dahaba, A. A.
    Metzler, H.
    [J]. MINERVA ANESTESIOLOGICA, 2009, 75 (7-8) : 447 - 452
  • [7] ROLE OF SERUM PROCALCITONIN AS MARKER OF NEONATAL SEPSIS
    Gupta, Pradeep
    Narang, Anil
    [J]. ARCHIVES OF DISEASE IN CHILDHOOD, 2019, 104 : A331 - A331
  • [8] Arginase and Procalcitonin: Promising Biomarkers for Early Diagnosis of Sepsis
    Mulgund, Shruti Rahul
    Abhang, Subodhini Anant
    [J]. JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2020, 14 (09)
  • [9] Role of Procalcitonin in the Early Diagnosis of Neonatal Sepsis
    Corona, G.
    Aversa, S.
    Decembrino, N.
    Giorgianni, G.
    Artemisia, A.
    Cordaro, V.
    Barberi, I.
    [J]. PROCEEDINGS OF THE XXI EUROPEAN CONGRESS OF PERINATAL MEDICINE, 2008, : 105 - +
  • [10] Potential Biomarkers for Early Diagnosis, Evaluation, and Prognosis of Sepsis-Induced Coagulopathy
    Li, Yuting
    Li, Hongxiang
    Wang, Youquan
    Guo, Jianxing
    Zhang, Dong
    [J]. CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS, 2023, 29