Synthesis and Biological Activity of Novel Phenyltriazolinone Derivatives

被引：12

作者：

Wu, Qiongyou ^{[1
]}

Wang, Guodong ^{[1
]}

Huang, Shaowei ^{[1
]}

Lin, Long ^{[1
]}

Yang, Guangfu ^{[1
]}

机构：

[1] Cent China Normal Univ, Coll Chem, Key Lab Pesticide & Chem Biol, Minist Educ, Wuhan 430079, Hubei, Peoples R China

来源：

MOLECULES | 2010年 / 15卷 / 12期

关键词：

phenyltriazolinones; strobilurin; herbicidal activity; protoporphyrinogen oxidase; OXIDASE-INHIBITORS; PROTOPORPHYRINOGEN; TRIAZOLONE; DELETION; DESIGN;

D O I：

10.3390/molecules15129024

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Phenyltriazolinones are one of the most important classes of herbicides targeting the protoporphyrinogen oxidase enzyme. A series of triazolinone derivatives containing a strobilurin pharmacophore were designed and synthesized with the aim of discovering new phenyltriazolinone analogues with high activity. The herbicidal activity of the synthesized compounds was assayed and some of the test compounds displayed moderate herbicidal activity at 150 g ai/ha.

引用

页码：9024 / 9034

页数：11

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