Trends in Hospitalization and In-Hospital Mortality From VTE, 2007 to 2016, in Chin

被引：83

作者：

Zhang, Zhu ^{[1
,3
,4
,5
]}

Lei, Jieping ^{[2
,3
]}

Shao, Xiang ^{[1
,3
,6
]}

Dong, Fen ^{[2
,3
]}

Wang, Jing ^{[1
,3
,7
]}

Wang, Dingyi ^{[2
,3
]}

Wu, Sinan ^{[2
,3
]}

Xie, Wanmu ^{[1
,3
]}

Wan, Jun ^{[1
,3
]}

Chen, Hong ^{[8
,20
]}

Ji, Yingqun ^{[9
,32
]}

Yi, Qun ^{[10
,37
]}

Xu, Xiaomao ^{[11
,16
]}

Yang, Yuanhua ^{[12
]}

Zhai, Zhenguo ^{[1
,3
]}

Wang, Chen ^{[1
,3
,4
,5
]}

Zhang, Jin ^{[13
]}

Zhang, Peng ^{[13
]}

Mao, Yimin ^{[14
]}

Yang, Xiaohong ^{[15
]}

Xu, Xiaomao ^{[11
,16
]}

Xia, Guoguang ^{[17
]}

Zheng, Rui ^{[17
]}

Gao, Yuan ^{[17
]}

Zhu, Guangfa ^{[18
]}

Zhu, Chenxi ^{[18
]}

Fu, Yingyun ^{[19
]}

Chen, Hong ^{[8
,20
]}

Yu, Fangfei ^{[20
]}

Kuang, Jiulong ^{[21
]}

Li, Ziqiang ^{[21
]}

Cheng, Zhe ^{[22
]}

Wu, Rui ^{[23
]}

Cheng, Zhaozhong ^{[24
]}

Tong, Li ^{[25
]}

Jiang, Yanwen ^{[26
]}

Sun, Jie ^{[26
]}

Xu, Qixia ^{[27
]}

Pan, Huiyun ^{[28
]}

Wang, Lihong ^{[28
]}

Zeng, Mian ^{[29
]}

Chen, Yanzhu ^{[29
]}

Yu, Chunxiao ^{[30
]}

Hua, Jing ^{[30
]}

Tang, Yongjun ^{[31
]}

Ji, Yingqun ^{[9
,32
]}

An, Jun ^{[32
]}

Zhang, Yongxiang ^{[33
]}

Ding, Yanyan ^{[33
]}

Zhang, Wei ^{[34
]}

机构：

[1] China Japan Friendship Hosp, Dept Pulm & Crit Care Med, Ctr Resp Med, Beijing, Peoples R China

[2] China Japan Friendship Hosp, Inst Clin Med Sci, Beijing, Peoples R China

[3] Natl Clin Res Ctr Resp Dis, Beijing, Peoples R China

[4] Chinese Acad Med Sci, Grad Sch, Peking Union Med Coll, Beijing, Peoples R China

[5] Peking Union Med Coll, Beijing, Peoples R China

[6] Beijing Univ Chinese Med, Beijing, Peoples R China

[7] Peking Univ, Hlth Sci Ctr, Beijing, Peoples R China

[8] Chongqing Med Univ, Dept Pulm & Crit Care Med, Affiliated Hosp 1, Chongqing, Peoples R China

[9] Dalian Med Univ, Affiliated Hosp 1, Dept Resp Med, Dalian, Liaoning, Peoples R China

[10] Sichuan Univ, Dept Pulm & Crit Med, West China Hosp, Chengdu, Sichuan, Peoples R China

[11] Beijing Hosp, Dept Pulm & Crit Care Med, Beijing, Peoples R China

[12] Capital Med Univ, Dept Pulm & Crit Care Med, Beijing Chaoyang Hosp, Beijing Inst Resp Med, Beijing, Peoples R China

[13] Ningxia Med Univ, Gen Hosp, Ningxia, Peoples R China

[14] Henan Univ Sci & Technol, Affiliated Hosp 1, Luoyang, Peoples R China

[15] Peoples Hosp Xinjiang Uygur Autonomous Reg, Xinjiang, Urumqi, Peoples R China

[16] Beijing Hosp, Beijing, Peoples R China

[17] China Med Univ, ShengJing Hosp, Shenyang, Liaoning, Peoples R China

[18] Beijing Anzhen Hosp, Beijing, Peoples R China

[19] Shenzhen Peoples Hosp, Shenzhen, Peoples R China

[20] Harbin Med Univ, Affiliated Hosp 2, Harbin, Heilongjiang, Peoples R China

[21] Nanchang Univ, Affiliated Hosp 2, Nanchang, Jiangxi, Peoples R China

[22] Zhengzhou Univ, Affiliated Hosp 1, Zhengzhou, Henan, Peoples R China

[23] Peking Univ, Hosp 3, Beijing, Peoples R China

[24] Qingdao Univ, Affiliated Hosp, Qingdao, Peoples R China

[25] Qingdao Univ, Affiliated Hosp, Qingdao, Peoples R China

[26] Beijing Shijitan Hosp, Beijing, Peoples R China

[27] Bengbu Med Coll, Affiliated Hosp 1, Bengbu, Peoples R China

[28] Zhejiang Univ, Affiliated Hosp 1, Hangzhou, Zhejiang, Peoples R China

[29] First Affiliated Hosp Sun Yat Sen, Guangzhou, Guangdong, Peoples R China

[30] Beijing Jingmei Hosp, Beijing, Peoples R China

[31] Cent South Univ, Xiangya Hosp, Changsha, Hunan, Peoples R China

[32] Dalian Med Univ, Affiliated Hosp 1, Dalian, Peoples R China

[33] Beijing Daxing Peoples Hosp, Beijing, Peoples R China

[34] Changhai Hosp Shanghai, Shanghai, Peoples R China

[35] Zhejiang Taizhou Hosp, Wenzhou, Zhejiang, Peoples R China

[36] Jinzhou Med Univ, Affiliated Hosp 1, Jinzhou, Peoples R China

[37] West China Hosp, Chengdu, Sichuan, Peoples R China

[38] North Sichuan Med Coll, Affiliated Hosp, Nanchong, Peoples R China

[39] Shanxi Prov Peoples Hosp, Taiyuan, Shanxi, Peoples R China

[40] Zhejiang Univ, Sir Run Run Shaw Hosp, Sch Med, Hangzhou, Zhejiang, Peoples R China

[41] Xi An Jiao Tong Univ, Affiliated Hosp 1, Xian, Shaanxi, Peoples R China

[42] PLA, Hosp 101, Wuxi, Peoples R China

[43] Beijing Tongren Hosp, Beijing, Peoples R China

[44] Shanghai Rui Jin Hosp, Shanghai, Peoples R China

[45] First Hosp Shijiazhuang, Shijiazhuang, Hebei, Peoples R China

[46] Shanxi Med Univ, Hosp 1, Taiyuan, Shanxi, Peoples R China

[47] Chengdu First Peoples Hosp, Chengdu, Sichuan, Peoples R China

[48] Zibo First Hosp, Zibo, Peoples R China

[49] Hebei Med Univ, Hosp 1, Shijiazhuang, Hebei, Peoples R China

[50] First Peoples Hosp Yichang, Yichang, Hubei, Peoples R China

来源：

CHEST | 2019年 / 155卷 / 02期

基金：

中国国家自然科学基金; 北京市自然科学基金;

关键词：

DVT; hospitalization rate; mortality; pulmonary embolism; VTE; VENOUS THROMBOEMBOLISM; PULMONARY-EMBOLISM; PROPHYLAXIS; RISK; ADMISSIONS; MANAGEMENT; THROMBOSIS;

D O I：

10.1016/j.chest.2018.10.040

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

BACKGROUND: VTE has emerged as a major public health problem. However, data on VTE burden in China are seldom reported. METHODS: This study collected data on patients with a principal diagnosis of VTE, pulmonary embolism (PE), or DVT by using the International Classification of Diseases, 10th Revision, from 90 hospitals across China. The trends in hospitalization rates, mortality, length of stay (LOS), and comorbidities from 2007 to 2016 were analyzed. RESULTS: In total, 105,723 patients with VTE were identified. For patients with VTE, the age-and sex-adjusted hospitalization rate increased from 3.2 to 17.5 per 100,000 population, and in-hospital mortality decreased from 4.7% to 2.1% (P < .001). The mean LOS declined from 14 to 11 days (P < .001). In addition, the data in 2016 showed that the hospitalization rate of VTE was higher in elderly male patients (male patients vs female patients, 155.3 vs 125.4 per 100,000 population in patients aged >= 85 years; P < .001) and in northern China (north vs south, 18.4 vs 13.4 per 100,000 population; P < .001). Higher mortality rates were found in patients with cancer and Charlson Comorbidity Index scores > 2. Similar trends were also observed in patients with PE and those with DVT. The hospitalization rate in China was much lower than that of the United States or selected sites in Canada and Europe, the LOS was much longer, and the in-hospital mortality rates were similar. CONCLUSIONS: The hospitalization rates of VTE increased steadily, and the mortality declined. This study provides important information on the disease burden of VTE in China.

引用

页码：342 / 353

页数：12

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