Strategies for the study of neuropsychiatric disorders using endophenotypes in developing countries: a potential databank from China

被引:8
|
作者
Chan, Raymond C. K. [1 ]
Gottesman, Irving I. [2 ,3 ]
Ge, Xiaojia [4 ]
Sham, Pak C. [5 ,6 ]
机构
[1] Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Neuropsychol & Appl Cognit Neurosci Lab, Beijing 100101, Peoples R China
[2] Univ Minnesota, Dept Psychiat, Dev Neuroimaging Lab, Minneapolis, MN 55455 USA
[3] Univ Minnesota, Dept Psychol, Dev Neuroimaging Lab, Minneapolis, MN 55455 USA
[4] Univ Minnesota, Inst Child Dev, Minneapolis, MN 55455 USA
[5] Univ Hong Kong, Dept Psychiat, Hong Kong, Hong Kong, Peoples R China
[6] Univ Hong Kong, State Key Lab Brain & Cognit Sci, Hong Kong, Hong Kong, Peoples R China
来源
基金
美国国家科学基金会;
关键词
endophenotypes; neuropsychiatric disorders; schizophrenia; neurological soft signs; NEUROLOGICAL SOFT SIGNS; NEUROCOGNITIVE ENDOPHENOTYPES; SCHIZOPHRENIA; ATTENTION; SUSCEPTIBILITY; HERITABILITY; EPIGENETICS; PHENOTYPES; CONSORTIUM; KNOWLEDGE;
D O I
10.3389/fnhum.2010.00207
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Endophenotypic research can be considered to be one of the most promising strategies to bridge the gap between genomic complexity and the phenotypic heterogeneity observed in neuropsychiatric disorders. However, despite the promising and systematic work initiated by our western counterparts, this research strategy is still not well known in developing countries. Thus, the purpose of this paper is to argue the merits and promise of a potentially useful database on phenotypes and endophenotypes for developing countries.
引用
收藏
页数:5
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