Transcripts, transcripts, everywhere - Commentary

被引：5
|
作者：
de Alava, E [1 ]
机构：
[1] Univ Navarra, Clin Univ Navarra, Dept Anat Patol, E-31080 Pamplona, Spain
来源：
ADVANCES IN ANATOMIC PATHOLOGY | 2001年 / 8卷 / 05期
关键词：
translocation; gene fusion; reverse transcription polymerase chain reaction fluorescence in situ hybridization; synovial sarcoma; malignant peripheral sheath tumor;
D O I：
10.1097/00125480-200109000-00003
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
A typical feature of many sarcomas is the consistent presence of balanced chromosomal translocations, originating novel gene fusions. Two recent reports show,acne fusions with reverse transcription polymerase chain reaction in two unexpected entities: EWS-FLI-1 in giant cell tumor of bone and SYT-SSX in malignant peripheral nerve sheath tumor. This commentary discusses several items that can be of help in performing a critical evaluation of these reports and similar ones.
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收藏
页码：264 / 272
页数：9
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