Phase diagram determination for phospholipid/sterol membranes using deuterium NMR

被引：20
|
作者：
Hsueh, YW
Zuckermann, M
Thewalt, J [1 ]
机构：
[1] Simon Fraser Univ, Dept Phys, Burnaby, BC V5A 1S6, Canada
[2] Natl Cent Univ, Dept Phys, Chungli 320, Taiwan
[3] Simon Fraser Univ, Dept Mol Biol & Biochem, Burnaby, BC V5A 1S6, Canada
来源：
CONCEPTS IN MAGNETIC RESONANCE PART A | 2005年 / 26A卷 / 01期
关键词：
phase diagram; phosphatidylcholine; ergosterol; H-2; NMR;
D O I：
10.1002/cmr.a.20034
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
Deuterium NMR is used to investigate the phase behavior of membranes containing ergosterol and to measure the temperature-ergosterol mole fraction phase diagram. In particular, our approach to analyzing the NMR spectra has allowed us to definitively locate and characterize the region where two liquid crystalline phases coexist. The general methodology for phase boundary determination in phospholipid/sterol membranes is presented. (c) 2005 Wiley Periodicals, Inc.
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页码：35 / 46
页数：12
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