Serological response in health care workers after a single dose of SARS-CoV-2 vaccine using six automated SARS-CoV-2 antibody assays

被引:2
|
作者
Cuykx, Matthias [1 ]
Mortele, Olivier [2 ]
Jansens, Hilde [1 ]
Schouwers, Sofie [2 ]
Meskal, Anissa [2 ]
Hoffbauer, Ilse [1 ]
Peeters, Bart [1 ]
机构
[1] Univ Hosp Antwerp, Lab Med, Edegem, Belgium
[2] Lab Med, GasthuisZusters Antwerp, Antwerp, Belgium
关键词
COVID-19; SARS-CoV-2; Serology; Vaccination;
D O I
10.1016/j.diagmicrobio.2021.115486
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Spike (S)-and nucleocapsid (N)-specific serological assay responses were determined before and/or after first dose SARS-CoV-2 vaccination in 22 individuals. S-specific assays quantified antibodies after vaccination with significant higher levels in participants with a previous infection. Be cautious combining N-/S-specific assay results, potentially differentiating post-infection/vaccination immunization as assay-specific N-anti-body waning was observed. (c) 2021 Elsevier Inc. All rights reserved.
引用
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页数:3
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