NOVEL MODELS TO STUDY CYTOCHROME P450 3A4 DEPENDENT METABOLISM IN VIVO

被引:0
|
作者
van Waterschoot, Robert A. B. [1 ]
van Herwaarden, Antonius E. [1 ]
Wagenaar, Els [1 ]
van der Kruijssen, Cornelia M. M. [1 ]
Beijnen, Jos H. [2 ]
Schinkel, Alfred H. [1 ]
机构
[1] Netherlands Canc Inst, Div Expt Therapy, NL-1066 CX Amsterdam, Netherlands
[2] Slotervaart Hosp, Dept Pharm & Pharmacol, Amsterdam, Netherlands
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
144
引用
收藏
页码:102 / 102
页数:1
相关论文
共 50 条
  • [1] Structures of cytochrome P450 3A4
    Scott, EE
    Halpert, JR
    TRENDS IN BIOCHEMICAL SCIENCES, 2005, 30 (01) : 5 - 7
  • [2] Involvement of human cytochrome P450 3A4 in the metabolism of vamidothion
    Mehmood, Z
    Kelly, DE
    Kelly, SL
    PESTICIDE SCIENCE, 1996, 46 (03): : 287 - 290
  • [3] Cytochrome P450 3A4 is the major enzyme responsible for the metabolism of laquinimod, a novel immunomodulator
    Tuvesson, H
    Hallin, I
    Persson, R
    Sparre, B
    Gunnarsson, PO
    Seidegård, J
    DRUG METABOLISM AND DISPOSITION, 2005, 33 (06) : 866 - 872
  • [4] Role of human cytochrome p450 3A4 in metabolism of medroxyprogesterone acetate
    Kobayashi, K
    Mimura, N
    Fujii, H
    Minami, H
    Sasaki, Y
    Shimada, N
    Chiba, K
    CLINICAL CANCER RESEARCH, 2000, 6 (08) : 3297 - 3303
  • [5] Molecular modeling of cytochrome P450 3A4
    Szklarz, GD
    Halpert, JR
    JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 1997, 11 (03) : 265 - 272
  • [6] Metabolism of organochlorine pesticides: The role of human cytochrome P450 3A4
    Mehmood, Z
    Williamson, MP
    Kelly, DE
    Kelly, SL
    CHEMOSPHERE, 1996, 33 (04) : 759 - 769
  • [7] Sertraline and cytochrome P450 3A4 in dysthymia
    Dunn, E
    Helpard, B
    Steiner, M
    BIOLOGICAL PSYCHIATRY, 1997, 41 : 116 - 116
  • [8] Molecular modeling of cytochrome P450 3A4
    Grazyna D. Szklarz
    James R. Halpert
    Journal of Computer-Aided Molecular Design, 1997, 11 : 265 - 272
  • [9] Molecular simulations of cytochrome P450 3A4
    Czapla, Luke
    Amaro, Rommie E.
    Kontoyianni, Maria
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 243
  • [10] Biotransformation of zafirlukast by cytochrome P450 3A4
    Skordos, KW
    Yost, GS
    DRUG METABOLISM REVIEWS, 2003, 35 : 49 - 49