Early-onset behavioral and synaptic deficits in a mouse model of Alzheimer's disease are reversed by inhibition of gamma secretase

被引：0
|
作者：
Pangalos, MN [1 ]
Jacobsen, JS [1 ]
Comery, TA [1 ]
Wu, CC [1 ]
Redwine, JM [1 ]
Arias, R [1 ]
Martone, R [1 ]
Aschmies, S [1 ]
Atchinson, KP [1 ]
Morrison, JH [1 ]
Marquis, K [1 ]
Floyd, BE [1 ]
Reinhart, PH [1 ]
机构：
[1] Wyeth Ayerst Res, Neurosci Discovery, Princeton, NJ 08543 USA
来源：
NEUROPSYCHOPHARMACOLOGY | 2005年 / 30卷
关键词：
D O I：
暂无
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
引用
收藏
页码：S80 / S80
页数：1
相关论文
共 50 条
  • [1] Early-onset behavioral and synaptic deficits in a mouse model of Alzheimer's disease
    Jacobsen, JS
    Wu, CC
    Redwine, JM
    Comery, TA
    Arias, R
    Bowlby, M
    Martone, R
    Morrison, JH
    Pangalos, MN
    Reinhart, PH
    Bloom, FE
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (13) : 5161 - 5166
  • [2] Calcineurin Inhibition Rescues Early Synaptic Plasticity Deficits in a Mouse Model of Alzheimer’s Disease
    Virve Cavallucci
    Nicola Berretta
    Annalisa Nobili
    Robert Nisticò
    Nicola B. Mercuri
    Marcello D’Amelio
    NeuroMolecular Medicine, 2013, 15 : 541 - 548
  • [3] Calcineurin Inhibition Rescues Early Synaptic Plasticity Deficits in a Mouse Model of Alzheimer's Disease
    Cavallucci, Virve
    Berretta, Nicola
    Nobili, Annalisa
    Nistico, Robert
    Mercuri, Nicola B.
    D'Amelio, Marcello
    NEUROMOLECULAR MEDICINE, 2013, 15 (03) : 541 - 548
  • [4] Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model
    Du, Heng
    Guo, Lan
    Yan, Shiqiang
    Sosunov, Alexander A.
    McKhann, Guy M.
    Yan, Shirley ShiDu
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2010, 107 (43) : 18670 - 18675
  • [5] Early-onset behavioral and neurochemical deficits in the genetic mouse model of phenylketonuria
    Fiori, Elena
    Oddi, Diego
    Ventura, Rossella
    Colamartino, Marco
    Valzania, Alessandro
    D'Amato, Francesca Romana
    Bruinenberg, Vibeke
    van der Zee, Eddy
    Puglisi-Allegra, Stefano
    Pascucci, Tiziana
    PLOS ONE, 2017, 12 (08):
  • [6] Subchronic Glucocorticoid Receptor Inhibition Rescues Early Episodic Memory and Synaptic Plasticity Deficits in a Mouse Model of Alzheimer's Disease
    Lante, Fabien
    Chafai, Magda
    Raymond, Elisabeth Fabienne
    Pereira, Ana Rita Salgueiro
    Mouska, Xavier
    Kootar, Scherazad
    Barik, Jacques
    Bethus, Ingrid
    Marie, Helene
    NEUROPSYCHOPHARMACOLOGY, 2015, 40 (07) : 1772 - 1781
  • [7] Subchronic Glucocorticoid Receptor Inhibition Rescues Early Episodic Memory and Synaptic Plasticity Deficits in a Mouse Model of Alzheimer’s Disease
    Fabien Lanté
    Magda Chafai
    Elisabeth Fabienne Raymond
    Ana Rita Salgueiro Pereira
    Xavier Mouska
    Scherazad Kootar
    Jacques Barik
    Ingrid Bethus
    Hélène Marie
    Neuropsychopharmacology, 2015, 40 : 1772 - 1781
  • [8] Age-dependent increase in lysosome-associated membrane protein 1 and early-onset behavioral deficits in APPSL transgenic mouse model of Alzheimer's disease
    Hashimoto, Tetsuya
    Ogino, Koichi
    Shin, Ryong-Woon
    Kitamoto, Tetsuyuki
    Kikuchi, Tetsuro
    Shimizu, Noriaki
    NEUROSCIENCE LETTERS, 2010, 469 (02) : 273 - 277
  • [9] Early-Onset and Robust Amyloid Pathology in a New Homozygous Mouse Model of Alzheimer's Disease
    Willuweit, Antje
    Velden, Joachim
    Godemann, Robert
    Manook, Andre
    Jetzek, Fritz
    Tintrup, Hartmut
    Kauselmann, Gunther
    Zevnik, Branko
    Henriksen, Gjermund
    Drzezga, Alexander
    Pohlner, Johannes
    Schoor, Michael
    Kemp, John A.
    von der Kammer, Heinz
    PLOS ONE, 2009, 4 (11):
  • [10] Presenilins and early-onset Alzheimer's disease
    van Duijn, CM
    Cruts, M
    Backhovens, H
    Theuns, J
    Van Gassen, G
    Hofman, A
    Van Broeckhoven, C
    AMERICAN JOURNAL OF HUMAN GENETICS, 1997, 61 (04) : A214 - A214
12345