Novel and efficient synthesis of N,N-Dialkylamino and O-alkylphenyl-2-(1-alkyl/phenyl-2-oxopropylidene) phosphonohydrazido oximes -: Potential marine fish toxin analogues.: Part 2

被引:2
|
作者
Kumar, Rajesh [1 ]
Gupta, Arvind K. [1 ]
Kaushik, Mahabir P. [1 ]
机构
[1] Def Res & Dev Estab, Proc Technol Dev Div, Gwalior 474002, Madhya Pradesh, India
关键词
hydrazides; alpha-ketooxime; marine fish toxin; phosphonohydrazido oximes; phenyl derivatives;
D O I
10.3390/12081632
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A novel and efficient method for the synthesis of NN-dialkylamino/O-alkyl phenyl-2-(1-alkyl/phenyl-2-oxopropylidene) phosphonohydrazido oximes 4 using activated silica has been developed. The reaction involves the condensation of substituted alpha-ketooxime and N,N-dialkylaminophenylphosphonohydrazides or O-alkylphenyl-phosphonohydrazides and gave the corresponding phosphonohydrazido oximes in excellent yields under mild conditions.
引用
收藏
页码:1632 / 1640
页数:9
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