RETRACTED: Two-/three-dimensional coordination polymers: structural characterization and treatment activity on ulcerative colitis by regulating inflammatory cytokines (Retracted article. See MAY, 2023)

In the current study, two new mixed-ligand coordination polymers with the chemical formulae of {[Co(L-1)(0.5)(oba)center dot DMF]center dot DMF center dot H2O} (1, L-1 = N,N '-bis(4-pyridylmethyl)-naphthalene diimide, H(2)oba = 4,4 '-oxydibenzoic acid) and [Co(L-2)(0.5)(OBA)](n) (2, L-2 = 1,6-bis(benzimidazolyl)hexane) have been successfully synthesized by the solvothermal reaction of H(2)oba with different flexible N-donor organic ligands in the presence of Co(NO3)(2)center dot 6H(2)O as the metal source. In addition, the biological functional evaluation of the complexes was performed on the ulcerative colitis (UC) model. First, the enzyme-linked immunosorbent assay detection kit was performed to measure the content of the pro-inflammatory cytokines and anti-inflammatory cytokines after complexes treatment. Next, the UC mice model was constructed and the body weight of the mice was measured and recorded at the 7th and 14th day after complexes treatment at the concentration of 5 mg/kg.