Asymmetric synthesis of α-methoxyarylacetic acid derivatives

被引：26
|
作者：
Prasad, KR [1 ]
Chandrakumar, A [1 ]
机构：
[1] Indian Inst Sci, Dept Organ Chem, Bangalore 560012, Karnataka, India
来源：
TETRAHEDRON-ASYMMETRY | 2005年 / 16卷 / 11期
关键词：
D O I：
10.1016/j.tetasy.2005.05.002
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Stereoselective synthesis of a series of 2-aryl-2-methoxyethanols was achieved from inexpensive chiral pool tartaric acid employing a diastereoselective reduction of a symmetrical 1,4-diaryldiketone as the key step. 2-Aryl-2-methoxyethanols were enantioselectively prepared in 80-90% yield (c) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1897 / 1900
页数：4
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