Synthesis and Crystal Structure of a New Mestranol Acetate

被引：1

作者：

Li, Hongqi ^{[1
]}

Qian, Haichuan ^{[1
]}

Li, Jinxing ^{[1
]}

Ma, Shuwen ^{[2
]}

机构：

[1] Donghua Univ, Minist Educ, Coll Chem Chem Engn & Biotechnol, Key Lab Sci & Technol Ecotext, Shanghai 201620, Peoples R China

[2] NW Minor Univ, Coll Life Sci & Engn, Fac Food Sci, Lanzhou 730030, Peoples R China

来源：

JOURNAL OF CHEMICAL CRYSTALLOGRAPHY | 2011年 / 41卷 / 08期

关键词：

Mestranol; Acetate; Synthesis; X-ray; Crystal structure; DEGRADATION; PRODUCTS;

D O I：

10.1007/s10870-011-0074-y

中图分类号：

O7 [晶体学];

学科分类号：

0702 ; 070205 ; 0703 ; 080501 ;

摘要：

A new mestranol acetate, 17 alpha-ethinyl-17-hydroxy-3-methoxyestra-1,3,5(10)-triene-6-one-17-acetate, was synthesized by an efficient three-step sequence starting from norethindrone. The structure of the new steroid was characterized by H-1 NMR, C-13 NMR, MS, IR spectrum and X-ray single crystal diffraction. It crystallizes in the triclinic system, space group P1. The molecules are arranged in a head-to-tail fashion without intra- and intermolecular hydrogen bonding.

引用

页码：1208 / 1213

页数：6

共 50 条

[1] Synthesis and Crystal Structure of a New Mestranol Acetate
Hongqi Li
Haichuan Qian
Jinxing Li
Shuwen Ma
Journal of Chemical Crystallography, 2011, 41 : 1208 - 1213
[2] SYNTHESIS AND CRYSTAL STRUCTURE OF PYRROLIDINONE COPPER ACETATE
Liang Bing GAN Chu Ping LUO Chun Hui HUANG Guang Xian XU Research Center of Rare Earth Chemistry
ChineseChemicalLetters, 1992, (12) : 1019 - 1022
[3] EPIMERIZATION OF MESTRANOL ACETATE ON ALUMINA
KANOJIA, RM
YARMCHUC.L
SCHEER, I
JOURNAL OF ORGANIC CHEMISTRY, 1974, 39 (15): : 2304 - 2306
[4] Synthesis,Crystal Structure and Antimicrobial Property of Dehydroabietylamine Acetate
李勇
结构化学, 2008, (09) : 1089 - 1092
[5] Synthesis, crystal structure and antimicrobial property of dehydroabietylamine acetate
Li Yong
CHINESE JOURNAL OF STRUCTURAL CHEMISTRY, 2008, 27 (09) : 1089 - 1092
[6] HEPATOTOXICITY OF MESTRANOL AND NORETHISTERONE ACETATE IN THE RAT
BRIGNONE, JA
DEBRIGNONE, CMC
DEDAVILA, MTG
KOCH, O
STOPPANI, AOM
MEDICINA-BUENOS AIRES, 1979, 39 (04) : 477 - 488
[7] Synthesis, crystal structure, and thermal behavior of dimethylgold(III) acetate
A. A. Bessonov
I. A. Baidina
N. B. Morozova
P. P. Semyannikov
S. V. Trubin
N. V. Gelfond
I. K. Igumenov
Journal of Structural Chemistry, 2007, 48 : 282 - 288
[8] Synthesis, crystal structure, and thermal behavior of dimethylgold(III) acetate
Bessonov, A. A.
Baidina, I. A.
Morozova, N. B.
Semyannikov, P. P.
Trubin, S. V.
Gelfond, N. V.
Igumenov, I. K.
JOURNAL OF STRUCTURAL CHEMISTRY, 2007, 48 (02) : 282 - 288
[9] Synthesis, crystal structure, and characterization of copper(II) acetate complex
Koo, BK
BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 2001, 22 (01) : 113 - 116
[10] Synthesis and crystal structure of a new binaphthylamide
Wang, YW
Liu, WS
Yu, KB
JOURNAL OF STRUCTURAL CHEMISTRY, 2003, 44 (06) : 1071 - 1075

← 1 2 3 4 5 →