Group B Streptococcus (GBS) Invasive Infections in Women of Childbearing Age, France, 2012-2020: GBS CC-17 Hypervirulence in Intrapartum Infections

被引：2

作者：

Plainvert, Celine ^{[1
,2
,3
]}

Salvy-Tabet, Yasmina de Saint ^{[1
]}

Dmytruk, Nicolas ^{[1
,2
]}

Frigo, Amandine ^{[1
,2
]}

Poyart, Claire ^{[1
,2
,3
,4
]}

Tazi, Asmaa ^{[1
,2
,3
,4
]}

机构：

[1] Univ Hosp Paris, French Natl Reference Ctr Streptococci, Dept Bacteriol, Ctr Cochin,Federat Hosp Univ Fighting Prematur, Paris, France

[2] Cochin Hosp, AP HP, Paris, France

[3] Cochin Inst, Inst Natl Sante & Rech Med U1016, CNRS, Unite Mixte Rech 8104,Team Bacteria & Perinatal, Paris, France

[4] Univ Paris, Paris, France

来源：

JOURNAL OF INFECTIOUS DISEASES | 2022年 / 226卷 / 03期

关键词：

group B Streptococcus; Streptococcus agalactiae; invasive infection; women of childbearing age; epidemiology; pregnancy; capsular serotype; CC-17; clone; MENINGITIS; DISEASE; SEPSIS;

D O I：

10.1093/infdis/jiac076

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Group B Streptococcus(GBS) infections in pregnancy mainly occur preterm and are highly associated with obstetrical and neonatal complications. The hypervirulent neonatal GBS CC-17 represents a risk factor for intrapartum infections. Group B Streptococcus (GBS) is the leading cause of neonatal infections and an important pathogen in pregnancy. However, the features of pregnancy-associated infections are poorly reported. We analyzed 336 cases of GBS invasive infections in women aged 18-50 years, including 242 (72.0%) pregnancy-associated infections. In pregnancy, most cases were intra-amniotic infections (55.8%), occurred preterm (61.3%), and were associated with obstetrical and neonatal complications (81.7%). The GBS clone CC-17 (18.8% of the cases) was overrepresented intrapartum (35.2%; odds ratio, 5.1 [95% confidence interval, 1.6-19.3]). This work highlights the burden of GBS and of the CC-17 clone infections during pregnancy.

引用

页码：541 / 545

页数：5

共 2 条

[1] GROUP-B STREPTOCOCCUS (GBS) AND NEONATAL INFECTIONS - THE CASE FOR INTRAPARTUM CHEMOPROPHYLAXIS
GARLAND, SM
FLIEGNER, JR
[J]. AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY, 1991, 31 (02): : 119 - 122
[2] Group B streptococcus neonatal invasive infections, France 2007-2012
Joubrel, C.
Tazi, A.
Six, A.
Dmytruk, N.
Touak, G.
Bidet, P.
Raymond, J.
Cuot, P. Trieu
Fouet, A.
Kerneis, S.
Poyart, C.
[J]. CLINICAL MICROBIOLOGY AND INFECTION, 2015, 21 (10) : 910 - 916

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