Chemoprophylaxis for HIV Prevention: New Opportunities and New Questions

被引：7
|
作者：
Mayer, Kenneth H. [1 ,2 ]
Venkatesh, Kartik K. [3 ]
机构：
[1] Brown Univ, Miriam Hosp, Div Infect Dis, Dept Med,Alpert Med Sch, Providence, RI 02906 USA
[2] Brown Univ, Miriam Hosp, Alpert Med Sch, Dept Community Hlth, Providence, RI 02906 USA
[3] Fenway Inst, Boston, MA USA
来源：
JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES | 2010年 / 55卷
关键词：
AIDS; ART; HIV; primary prevention; preexposure prophylaxis; postexposure prophylaxis; topical microbicides; NONOCCUPATIONAL POSTEXPOSURE PROPHYLAXIS; SIMIAN IMMUNODEFICIENCY VIRUS; PREEXPOSURE PROPHYLAXIS; ANTIRETROVIRAL THERAPY; LIMITED KNOWLEDGE; SEMINAL PLASMA; UNITED-STATES; TRANSMISSION; TENOFOVIR; INFECTION;
D O I：
10.1097/QAI.0b013e3181fbcb4c
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Growing data suggest that antiretrovirals can be used as an effective means of HIV prevention. This article reviews the current status and future clinical prospects of utilizing antiretroviral chemoprophylaxis before and after high-risk HIV exposure to prevent HIV transmission. The discussion about using antiretrovirals as a means of primary HIV prevention has moved to the forefront of public health discourse because of a growing evidence base, the increased tolerability of the medications, the decreased cost, the ever-expanding formulary, and the limitations of other approaches.
引用
收藏
页码：S122 / S127
页数：6
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