A comparison of two- and four-electrode techniques to characterize blood impedance for the frequency range of 100 Hz to 100 MHz

被引：25

作者：

Chang, Zu-yao ^{[1
]}

Pop, Gheorghe A. M. ^{[2
]}

Meijer, Gerard C. M. ^{[1
]}

机构：

[1] Delft Univ Technol, Elect Instrumentat Lab, NL-2628 CD Delft, Netherlands

[2] Heartctr UMCN St Radboud, NL-6500 HB Nijmegen, Netherlands

来源：

IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING | 2008年 / 55卷 / 03期

关键词：

blood impedance; cell membrane capacitance; electrical model of blood; three-element model; two- and four-electrode techniques;

D O I：

10.1109/TBME.2008.915725

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Measurement setups that characterize the impedance of suspensions of blood over the wide frequency range of 100 Hz to 100 MHz are presented in this paper. The performance of the two- and four-electrode techniques have been compared and evaluated. By applying a combination of the two measurement techniques the best result is achieved when taking into account the main nonidealities, such as electrode polarization impedance and parasitic capacitances. It has been found that the conventional three-element model for the impedance of blood can be used for frequencies up to 1 MHz. For frequencies exceeding 1 MHz, an extended model is introduced where a constant phase angle element is used for modeling the cell membrane and a capacitor C-liq is added for modeling the electrical capacitance of water in blood.

引用

页码：1247 / 1249

页数：3

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