Sputum adenosine deaminase and alkaline phosphatase activity in pulmonary tuberculosis

被引：11

作者：

Jadhav, Ashish Anantrao ^{[1
]}

Jain, Anuradha

机构：

[1] Peoples Coll Med Sci, Dept Biochem, Bhopal, Madhya Pradesh, India

来源：

ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY | 2012年 / 118卷 / 01期

关键词：

Pulmonary tuberculosis; adenosine deaminase; alkaline phosphatase; sputum; BRONCHOALVEOLAR LAVAGE FLUID; DIAGNOSTIC-VALUE; DIFFERENTIATION; EFFUSIONS;

D O I：

10.3109/13813455.2011.645545

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Objective: The aim was to determine adenosine deaminase (ADA) and alkaline phosphatase (ALP) activity in sputum for the diagnosis of pulmonary tuberculosis. Methods: This study comprised of 64 subjects (33 pulmonary tuberculosis and 31 lung cancer). The ADA and ALP activity was measured in sputum and serum. Results: The mean ADA activity in sputum, serum and mean sputum/serum ADA ratio was 205.20 IU/L, 42.32 IU/L and 4.90 in pulmonary tuberculosis and 127.74 IU/L, 29.90 IU/L and 4.27 in lung cancer subjects respectively. The mean ALP activity in sputum, serum and mean sputum/serum ALP ratio was 461.34 IU/L, 159.24 IU/L and 2.90 in pulmonary tuberculosis and 226.64 IU/L, 119.87 IU/L and 1.99 in lung cancer subjects respectively. Conclusion: The mean ADA and ALP activity was significantly increased in pulmonary tuberculosis as compared to lung cancer subjects and hence may be a useful tool for the diagnosis of pulmonary tuberculosis.

引用

页码：6 / 9

页数：4

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