Effects of electron beam irradiation on microbial contamination and quality of Shengmai Yin

被引：2
|
作者：
Wang, Gang [1 ]
Wang, Dan [1 ]
Mei, Xingyue [1 ]
Huang, Min [2 ,3 ]
Zhang, Li [4 ]
Li, Xuemei [4 ]
机构：
[1] Southwest Univ Sci & Technol, Coll Life Sci & Engn, Mianyang 21010, Sichuan, Peoples R China
[2] Sichuan Inst Atom Energy, Chengdu 610101, Sichuan, Peoples R China
[3] Irradiat Preservat Key Lab Sichuan Prov, Chengdu 610101, Sichuan, Peoples R China
[4] Sichuan Mianyang Pharmaceut Co Ltd, Taiji Grp, Mianyang 621010, Sichuan, Peoples R China
来源：
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY | 2022年 / 331卷 / 09期
关键词：
Shengmai Yin (SMY); Decontamination by electron beam irradiation; Quality; Active ingredients; High-performance liquid chromatogram (HPLC); Attenuated total reflectance fourier-transform infrared (ATR-FTIR); GAMMA-IRRADIATION; STERILIZATION; DECONTAMINATION; FORMULATIONS; DEGRADATION; RADIATION; PRODUCTS; WATER;
D O I：
10.1007/s10967-022-08429-4
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
In this study, Shengmai Yin (SMY) was irradiated at doses of 2, 3, 5, and 7 kGy of electron-beam, to investigate the effects of electron beam irradiation (EBI) on the microbial content, color, active ingredients, and spectrogram similarity. Results showed that SMY was decontaminated at 7 kGy irradiation, but its color and active ingredients were altered. The similarity of the chromatogram was significantly altered at >= 5 kGy. Fourier transforms infrared spectra demonstrated the effect of EBI on the molecular structure. This study concluded that 7 kGy irradiation controls microbial limits for SMY but has an impact on quality.
引用
收藏
页码：3927 / 3933
页数：7
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