Landscape of Somatic Mutations Involving Lung Cancer Associated Genes in Non-Small Cell Lung Cancer (NSCLC) Patient-Derived Xenografts

被引:0
|
作者
Raghavan, Vibha [1 ]
Tam, Shirley [1 ]
Nhu-An Pham [1 ]
Li, Ming [1 ]
Shepherd, Frances [2 ,3 ]
Liu, Geoffrey [2 ,3 ]
Tsao, Ming [3 ,4 ]
机构
[1] Princess Margaret Canc Ctr, Toronto, ON, Canada
[2] Princess Margaret Canc Ctr, Dept Med Oncol & Haematol, Toronto, ON, Canada
[3] Univ Toronto, Toronto, ON, Canada
[4] Princess Margaret Canc Ctr, Dept Pathol, Toronto, ON, Canada
关键词
Somatic mutations; PDX; whole-exome sequencing; NSCLC;
D O I
10.1016/j.jtho.2016.11.519
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
MA17.06
引用
收藏
页码:S444 / S445
页数:2
相关论文
共 50 条
  • [1] Gene mutations in primary tumors and corresponding patient-derived xenografts derived from non-small cell lung cancer
    Hao, Chuncheng
    Wang, Li
    Peng, Shaohua
    Cao, Mengru
    Li, Hongyu
    Hu, Jing
    Huang, Xiao
    Liu, Wei
    Zhang, Hui
    Wu, Shuhong
    Pataer, Apar
    Heymach, John V.
    Eterovic, Agda Karina
    Zhang, Qingxiu
    Shaw, Kenna R.
    Chen, Ken
    Futreal, Andrew
    Wang, Michael
    Hofstetter, Wayne
    Mehran, Reza
    Rice, David
    Roth, Jack A.
    Sepesi, Boris
    Swisher, Stephen G.
    Vaporciyan, Ara
    Walsh, Garrett L.
    Johnson, Faye M.
    Fang, Bingliang
    CANCER LETTERS, 2015, 357 (01) : 179 - 185
  • [2] Tumor characteristics associated with engraftment of patient-derived non-small cell lung cancer xenografts in immunocompromised mice
    Chen, Yungchang
    Zhang, Ran
    Wang, Li
    Correa, Arlene M.
    Pataer, Apar
    Xu, Yi
    Zhang, Xiaoshan
    Ren, Chenghui
    Wu, Shuhong
    Meng, Qing H.
    Fujimoto, Junya
    Jensen, Vanessa B.
    Antonoff, Mara B.
    Hofstetter, Wayne L.
    Mehran, Reza J.
    Pisimisis, George
    Rice, David C.
    Sepesi, Boris
    Vaporciyan, Ara A.
    Walsh, Garrett L.
    Swisher, Stephen G.
    Roth, Jack A.
    Heymach, John, V
    Fang, Bingliang
    CANCER, 2019, 125 (21) : 3738 - 3748
  • [3] Generation of Non-Small Cell Lung Cancer Patient-Derived Xenografts to Study Intratumor Heterogeneity
    Kanaki, Zoi
    Voutsina, Alexandra
    Markou, Athina
    Pateras, Ioannis S.
    Potaris, Konstantinos
    Avgeris, Margaritis
    Makrythanasis, Periklis
    Athanasiadis, Emmanouil I.
    Vamvakaris, Ioannis
    Patsea, Eleni
    Vachlas, Konstantinos
    Lianidou, Evi
    Georgoulias, Vassilis
    Kotsakis, Athanasios
    Klinakis, Apostolos
    CANCERS, 2021, 13 (10)
  • [4] Integrative analysis of non-small cell lung cancer patient-derived xenografts identifies distinct proteotypes associated with patient outcomes
    Mirhadi, Shideh
    Tam, Shirley
    Li, Quan
    Moghal, Nadeem
    Pham, Nhu-An
    Tong, Jiefei
    Golbourn, Brian J.
    Krieger, Jonathan R.
    Taylor, Paul
    Li, Ming
    Weiss, Jessica
    Martins-Filho, Sebastiao N.
    Raghavan, Vibha
    Mamatjan, Yasin
    Khan, Aafaque A.
    Cabanero, Michael
    Sakashita, Shingo
    Huo, Kugeng
    Agnihotri, Sameer
    Ishizawa, Kota
    Waddell, Thomas K.
    Zadeh, Gelareh
    Yasufuku, Kazuhiro
    Liu, Geoffrey
    Shepherd, Frances A.
    Moran, Michael F.
    Tsao, Ming-Sound
    NATURE COMMUNICATIONS, 2022, 13 (01)
  • [5] Integrative analysis of non-small cell lung cancer patient-derived xenografts identifies distinct proteotypes associated with patient outcomes
    Shideh Mirhadi
    Shirley Tam
    Quan Li
    Nadeem Moghal
    Nhu-An Pham
    Jiefei Tong
    Brian J. Golbourn
    Jonathan R. Krieger
    Paul Taylor
    Ming Li
    Jessica Weiss
    Sebastiao N. Martins-Filho
    Vibha Raghavan
    Yasin Mamatjan
    Aafaque A. Khan
    Michael Cabanero
    Shingo Sakashita
    Kugeng Huo
    Sameer Agnihotri
    Kota Ishizawa
    Thomas K. Waddell
    Gelareh Zadeh
    Kazuhiro Yasufuku
    Geoffrey Liu
    Frances A. Shepherd
    Michael F. Moran
    Ming-Sound Tsao
    Nature Communications, 13
  • [6] Development and characterization of patient-derived xenografts from non-small cell lung cancer brain metastases
    Baschnagel, Andrew M.
    Kaushik, Saakshi
    Durmaz, Arda
    Goldstein, Steve
    Ong, Irene M.
    Abel, Lindsey
    Clark, Paul A.
    Gurel, Zafer
    Leal, Ticiana
    Buehler, Darya
    Iyer, Gopal
    Scott, Jacob G.
    Kimple, Randall J.
    SCIENTIFIC REPORTS, 2021, 11 (01)
  • [7] Establishment of Patient-Derived Non-Small Cell Lung Cancer Xenografts as Models for the Identification of Predictive Biomarkers
    Fichtner, Iduna
    Rolff, Jana
    Soong, Richie
    Hoffmann, Jens
    Hammer, Stefanie
    Sommer, Anette
    Becker, Michael
    Merk, Johannes
    CLINICAL CANCER RESEARCH, 2008, 14 (20) : 6456 - 6468
  • [8] Development and characterization of patient-derived xenografts from non-small cell lung cancer brain metastases
    Andrew M. Baschnagel
    Saakshi Kaushik
    Arda Durmaz
    Steve Goldstein
    Irene M. Ong
    Lindsey Abel
    Paul A. Clark
    Zafer Gurel
    Ticiana Leal
    Darya Buehler
    Gopal Iyer
    Jacob G. Scott
    Randall J. Kimple
    Scientific Reports, 11
  • [9] MicroRNA landscape in non-small cell lung cancer (NSCLC).
    Morgensztern, Daniel
    Devarakonda, Siddhartha H. K.
    Awh, Caroline
    Guebert, Kalin
    Maher, Christopher
    Maggi, Leonard B.
    Waqar, Saiama Naheed
    Carpenter, Danielle
    Robertson, Gordon
    Link, Daniel C.
    Govindan, Ramaswamy
    JOURNAL OF CLINICAL ONCOLOGY, 2014, 32 (15)
  • [10] Genomic Profiling of Patient-Derived Xenografts Identify Passenger Aberrations Associated with Better Prognosis in Non-Small Cell Lung Cancer
    Pham, Nhu-An
    Wang, Dennis
    Sakashita, Shingo
    Allo, Ghassan
    Kim, Lucia
    Yanagawa, Naoki
    Zhu, Chang-Qi
    Li, Ming
    Kaufman, Ethan
    Moghal, Nadeem
    Liu, Geoffrey
    Pintilie, Melania
    Jurisica, Igor
    McPherson, John D.
    Shepherd, Frances
    Tsao, Ming S.
    JOURNAL OF THORACIC ONCOLOGY, 2015, 10 (09) : S313 - S314