A novel symmetric sulfur-containing biscembranoid from the Formosan soft coral Sinularia flexibilis

被引：41
|
作者：
Chen, Bo-Wei [1 ]
Chao, Chih-Hua [1 ]
Su, Jui-Hsin [2 ]
Huang, Chiung-Yao [1 ]
Dai, Chang-Feng [3 ]
Wen, Zhi-Hong [1 ,4 ]
Sheu, Jyh-Horng [1 ,4 ]
机构：
[1] Natl Sun Yat Sen Univ, Dept Marine Biotechnol & Resources, Kaohsiung 804, Taiwan
[2] Natl Museum Marine Biol & Aquarium, Taiwan Coral Res Ctr, Checheng 944, Pingtung, Taiwan
[3] Natl Taiwan Univ, Inst Oceanog, Taipei 112, Taiwan
[4] Natl Sun Yat Sen Univ, Asia Pacific Ocean Res Ctr, Kaohsiung 804, Taiwan
来源：
TETRAHEDRON LETTERS | 2010年 / 51卷 / 44期
关键词：
Soft coral; Sinularia flexibilis; Thioflexibilolide A; Anti-inflammatory activity; Neuroprotective activity; TERPENOIDS; LOCHMODES;
D O I：
10.1016/j.tetlet.2010.08.027
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A structurally unique symmetric sulfur-containing biscembranoid, namely, thioflexibilolide A (1), was isolated from the soft coral Sinularia flexibilis. The structure was determined by extensive spectroscopic analyses. Compound 1 has been found to possess significant anti-inflammatory and neuroprotective activities. (C) 2010 Elsevier Ltd. All rights reserved.
引用
收藏
页码：5764 / 5766
页数：3
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