Naked-Eye Detection of Aluminum in Gastric Drugs on a Paper-Based Analytical Device

被引:11
|
作者
Lai, Heyun [1 ]
Li, Ziqi [1 ]
Zhu, Shunying [1 ]
Cai, Longfei [1 ]
Xu, Chunxiu [1 ]
Zhou, Qing [2 ]
机构
[1] Hanshan Normal Univ, Sch Chem & Environm Engn, Chaozhou 521041, Guangdong, Peoples R China
[2] Shaanxi Normal Univ, Sch Chem & Chem Engn, Xian 710119, Shaanxi, Peoples R China
关键词
Upper-Division Undergraduate; Analytical Chemistry; Hands-On Learning/Manipulatives; Microscale Lab; Quantitative Analysis; MICROFLUIDIC DEVICE; THREAD; IMMUNOASSAY;
D O I
10.1021/acs.jchemed.9b00569
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
This communication describes a method to detect aluminum in gastric drugs by the naked eye using a microfluidic paper-based analytical device (mu PAD). Aluminum ions react with chrome azurol S (CAS) and cetyltrimethylammonium bromide (CTAB) to form a colored complex, which generates a colored band on the mu PAD. A printed ruler can be used to measure the length of the colored band on an individual paper channel for the quantification of an aluminum ion. The mu PAD system was designed for use in a modern instrumental analysis course taken by students majoring in Food Quality and Safety. This analytical protocol could also be modified to be used as a demonstration or laboratory experiment in a high school chemistry course with some simplifications to the procedures.
引用
收藏
页码:295 / 299
页数:9
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