Structural and functional analysis of the role of the chaperonin CCT in the stability LCA-associated RPE65 mutants

被引：0
|
作者：
Smith, Theresa
Read, Kristen
Shen, Peter
Stewart, Michael
Kiser, Philip
Willardson, Barry
机构：
来源：
FASEB JOURNAL | 2021年 / 35卷
关键词：
D O I：
10.1096/fasebj.2021.35.S1.02450
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页数：1
相关论文
共 23 条
  • [1] Structural and Functional Analysis of RPE65 Folding by the Cytosolic Chaperonin CCT
    Smith, Theresa
    Stewart, Michael
    Read, Kristen
    Shen, Peter
    Willardson, Barry
    FASEB JOURNAL, 2020, 34
  • [2] Dissecting the Functional Role of Palmitoylation on RPE65 Protein
    Uppal, Sheetal
    Liu, Tingting
    Poliakov, Eugenia
    Gentleman, Susan
    Redmond, Thomas M.
    BIOPHYSICAL JOURNAL, 2020, 118 (03) : 242A - 242A
  • [3] Structural and functional analysis of the role of the chaperonin CCT in mTOR complex assembly
    Cuellar, J.
    Ludlam, W. G.
    Tensmeyer, N. C.
    Aoba, T.
    Dhavale, M.
    Santiago, C.
    Bueno-Carrasco, M. T.
    Mann, M. J.
    Plimpton, R. L.
    Makaju, A.
    Franklin, S.
    Willardson, B. M.
    Valpuesta, J. M.
    EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 2019, 48 : S129 - S129
  • [4] Low temperature-dependent functional rescue of RPE65 mutants associated with retinal degeneration
    Jin, Minghao
    Li, Songhua
    Hu, Jane
    Jin, Robin J.
    Jacobson, Samuel G.
    Bok, Dean
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2015, 56 (07)
  • [5] Structural and functional analysis of the role of the chaperonin CCT in mTOR complex assembly
    Willardson, Barry
    Cuellar, Jorge
    Ludlam, Grant
    Tensmeyer, Nicole
    Aoba, Takuma
    Dhavale, Madhura
    Santiago, Cesar
    Bueno-Carrasco, Teresa
    Mann, Michael
    Plimpton, Rebecca
    Makaju, Aman
    Franklin, Sarah
    FASEB JOURNAL, 2020, 34
  • [6] Structural and functional analysis of the role of the chaperonin CCT in mTOR complex assembly
    Cuellar, Jorge
    Ludlam, W. Grant
    Tensmeyer, Nicole C.
    Aoba, Takuma
    Dhavale, Madhura
    Santiago, Cesar
    Bueno-Carrasco, M. Teresa
    Mann, Michael J.
    Plimpton, Rebecca L.
    Makaju, Aman
    Franklin, Sarah
    Willardson, Barry M.
    Valpuesta, Jose M.
    NATURE COMMUNICATIONS, 2019, 10 (1)
  • [7] Structural and functional analysis of the role of the chaperonin CCT in mTOR complex assembly
    Jorge Cuéllar
    W. Grant Ludlam
    Nicole C. Tensmeyer
    Takuma Aoba
    Madhura Dhavale
    César Santiago
    M. Teresa Bueno-Carrasco
    Michael J. Mann
    Rebecca L. Plimpton
    Aman Makaju
    Sarah Franklin
    Barry M. Willardson
    José M. Valpuesta
    Nature Communications, 10
  • [8] Functional Rescue of Retinal Degeneration-Associated Mutant RPE65 Proteins
    Jin, Minghao
    Li, Songhua
    Hu, Jane
    Jin, Heather H.
    Jacobson, Samuel G.
    Bok, Dean
    RETINAL DEGENERATIVE DISEASES: MECHANISMS AND EXPERIMENTAL THERAPY, 2016, 854 : 525 - 532
  • [9] Temperature-sensitive retinoid isomerase activity of RPE65 mutants associated with Leber Congenital Amaurosis
    Li, Songhua
    Hu, Jane
    Jin, Robin J.
    Aiyar, Ashok
    Jacobson, Samuel G.
    Bok, Dean
    Jint, Minghao
    JOURNAL OF BIOCHEMISTRY, 2015, 158 (02): : 115 - 125
  • [10] Functional and structural recovery of the retina after gene therapy in the RPE65 null mutation dog
    Narfström, K
    Katz, ML
    Bragadottir, R
    Seeliger, M
    Boulanger, A
    Redmond, TM
    Caro, L
    Lai, CM
    Rakoczy, PE
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2003, 44 (04) : 1663 - 1672
123