Increased cardiovascular risk in patients with rheumatoid arthritis: an overview

被引：18

作者：

Puttevils, Daisy ^{[1
]}

De Vusser, Philip ^{[2
]}

Geusens, Piet ^{[3
]}

Dens, Jo ^{[2
]}

机构：

[1] Leuven Univ Hosp, Dept Cardiol, B-3000 Leuven, Belgium

[2] Ziekenhuis Oost Limburg, Dept Cardiol, Genk, Belgium

[3] Netherlands & Univ Hasselt, Maastricht Univ Med Ctrdep, Dept Rheumatol, Hasselt, Belgium

来源：

ACTA CARDIOLOGICA | 2014年 / 69卷 / 02期

关键词：

Cardiovascular risk; atherogenesis; rheumatoid arthritis; TNF antagonists; heart failure; NECROSIS-FACTOR-ALPHA; CONGESTIVE-HEART-FAILURE; IMPROVES ENDOTHELIAL FUNCTION; C-REACTIVE PROTEIN; CAUSE-SPECIFIC MORTALITY; LONG-TERM TREATMENT; ANTI-TNF THERAPY; INSULIN-RESISTANCE; INFLAMMATORY POLYARTHRITIS; MYOCARDIAL-INFARCTION;

D O I：

10.1080/AC.69.2.3017291

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Patients with established rheumatoid arthritis (RA) have a higher cardiovascular morbidity and mortality in comparison with the general population. It is considered to be an independent risk factor for cardiovascular disease. The purpose of this article is to describe the mechanisms responsible for accelerated atherogenesis in RA patients and to give an overview of the effects of different RA therapies (methotrexate, TNF antagonists and other biologicals).

引用

页码：111 / 118

页数：8

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