A model for wetting and evaporation of a post-blink precorneal tear film

被引:42
|
作者
Winter, Katlyn N. [1 ]
Anderson, Daniel M. [1 ]
Braun, Richard J. [2 ]
机构
[1] George Mason Univ, Dept Math Sci, Fairfax, VA 22030 USA
[2] Univ Delaware, Dept Math Sci, Newark, DE 19716 USA
基金
美国国家科学基金会;
关键词
tear film; evaporation; van der Waals; wetting; CORNEAL MUCUS LAYER; DRY EYE DISEASE; RUPTURE; THICKNESS; DYNAMICS; SURFACE; SUBCOMMITTEE; DEPOSITION; HYDRATION; PRESSURE;
D O I
10.1093/imammb/dqp019
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
We examine a fluid dynamic model for the evolution of a precorneal tear film that includes evaporation of the aqueous layer and a wetting corneal surface. Our model extends previous work on the break-up time for a post-blink tear film to include a more realistic model for evaporation. The evaporation model includes the effects of conjoining pressure and predicts the existence of an equilibrium adsorbed fluid layer that serves as a model for a wetting corneal surface/mucin layer. The model allows the prediction of dewetting rates that are compared with experimental measurements. By choosing an expected thickness where evaporation and conjoining pressure balance, we obtain qualitative agreement for the opening rate with in vivo observations.
引用
收藏
页码:211 / 225
页数:15
相关论文
共 50 条
  • [1] Tear spreading rates: Post-blink
    Owens, H
    Phillips, JR
    [J]. LACRIMAL GLAND, TEAR FILM, AND DRY EYE SYNDROMES 3: BASIC SCIENCE AND CLINICAL RELEVANCE, PTS A & B, 2002, 506 : 1201 - 1204
  • [2] Modelling drainage of the precorneal tear film after a blink
    Braun, RJ
    Fitt, AD
    [J]. MATHEMATICAL MEDICINE AND BIOLOGY-A JOURNAL OF THE IMA, 2003, 20 (01): : 1 - 28
  • [3] Post-blink tear film dynamics in healthy and dry eyes during spontaneous blinking
    Szczesna-Iskander, Dorota H.
    [J]. OCULAR SURFACE, 2018, 16 (01): : 93 - 100
  • [4] Evaporation-driven instability of the precorneal tear film
    Peng, Cheng-Chun
    Cerretani, Colin
    Braun, Richard J.
    Radke, C. J.
    [J]. ADVANCES IN COLLOID AND INTERFACE SCIENCE, 2014, 206 : 250 - 264
  • [5] A new method for post-blink tear film leveling analysis in healthy and dry eyes during spontaneous blinking
    Szczesna-Iskander, Dorota Helena
    Sulot, Dominika
    [J]. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2023, 64 (08)
  • [6] EVAPORATION RATE OF WATER FROM PRECORNEAL TEAR FILM AND CORNEA IN RABBIT
    IWATA, S
    LEMP, MA
    HOLLY, FJ
    DOHLMAN, CH
    [J]. INVESTIGATIVE OPHTHALMOLOGY, 1969, 8 (06): : 613 - &
  • [7] SURFACE-TENSION GRADIENT MECHANISM FOR DRIVING PRECORNEAL TEAR FILM AFTER A BLINK
    BERGER, RE
    CORRSIN, S
    [J]. JOURNAL OF BIOMECHANICS, 1974, 7 (03) : 225 - &
  • [8] PRECORNEAL TEAR FILM, STRUCTURE AND STABILITY
    PROUST, JE
    ARENAS, E
    PETROUTSOS, G
    POULIQUEN, Y
    [J]. JOURNAL FRANCAIS D OPHTALMOLOGIE, 1983, 6 (12): : 963 - 969
  • [9] Association of precorneal and preconjunctival tear film
    Takehisa, Y
    Yokoi, N
    Komuro, A
    Kinoshita, S
    [J]. LACRIMAL GLAND, TEAR FILM, AND DRY EYE SYNDROMES 2: BASIC SCIENCE AND CLINICAL RELEVANCE, 1998, 438 : 407 - 410
  • [10] The stability of corneal topography in the post-blink interval
    Buehren, T
    Collins, MJ
    Iskander, DR
    Davis, B
    Lingelbach, B
    [J]. CORNEA, 2001, 20 (08) : 826 - 833