Tilted fibre Bragg gratings for the specific detection of biological species

被引：3
|
作者：
Maguis, Severine [1 ]
Laffont, Guillaume [1 ]
Ferdinand, Pierre [1 ]
Millot, Marie-C. [2 ]
Kham, Khemara [2 ]
Peralta, Sebastien [3 ]
机构：
[1] Ctr Etud Saclay, Lab Mesures Opt, LIST, CEA, F-91191 Gif Sur Yvette, France
[2] Univ Paris 12, CNRS, Equipe Syst Polymeres Complexes, ICMPE,UMR 7182, F-94320 Thiais, France
[3] Univ Cergy Pontoise, Lab Phys Chim Polymeres & Interfaces, F-95031 Cergy Pontoise, France
来源：
19TH INTERNATIONAL CONFERENCE ON OPTICAL FIBRE SENSORS, PTS 1 AND 2 | 2008年 / 7004卷
关键词：
fibre Bragg grating; optical fibre biosensor; thin film; self-assembled layers; measurement method;
D O I：
10.1117/12.786044
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
We present a study aimed at developing fibre-optic-based biosensors for the specific detection of biological species. These sensors rely on the combined use of a Tilted short period Fibre Bragg Grating that detects changes in the refractive index of the surrounding solution and of an electrostatic self-assembly technique: self-assembled polyelectrolyte layers and immobilization of the sensor protein on the fibre surface were used for sensor fabrication. We observed changes in the sensor's spectrum induced by specific binding and we imaged fibre surface with atomic force microscopy (AFM). The results show the feasibility of the sensor for various biological or chemical applications.
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页数：4
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