MEPE-derived ASARM an inhibitor of calciprotein particle formation, suppresses vascular calcification but not bone formation

被引:0
|
作者
Kharaghani, Davood [1 ]
Minamizaki, Tomoko [1 ]
Kohno, Shohei [1 ]
Hoshino, Tomonori [1 ]
Yoshimori, Atsushi [2 ]
Yoshiko, Yuji [1 ]
机构
[1] Hiroshima Univ, Grad Sch Biomed & Hlth Sci, Dept Calcified Tissue Biol, Minami Ku, 1-2-3 Kasumi, Hiroshima 7348553, Japan
[2] Inst Theoret Med Inc, 26-1,Muraoka Higashi 2 chome, Fujisawa, Kanagawa 2510012, Japan
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
SUN-262
引用
收藏
页码:314 / 314
页数:1
相关论文
共 50 条
  • [1] MEPE-derived ASARM peptide selectively inhibits vascular calcification
    Kohno, Shohei
    Minamizaki, Tomoko
    Kharaghani, Davood
    Hoshino, Tomonori
    Yoshiko, Yuji
    JOURNAL OF BONE AND MINERAL RESEARCH, 2023, 38 : 225 - 225
  • [2] Sucroferric Oxyhydroxide Therapy Reduces Endogenous Calciprotein Particle Formation in Dialysis Patients and Attenuates Calcification and Inflammation in Vascular Cells In Vitro
    Thiem, Ursula
    Hewitson, Timothy D.
    Toussaint, Nigel D.
    Holt, Stephen G.
    Haller, Maria C.
    Pasch, Andreas
    Cejka, Daniel
    Smith, Edward R.
    JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2022, 33 (11): : 650 - 650
  • [3] A SYNTHETIC PEPTIDE DERIVED FROM THE SIBLING PROTEIN MEPE INHIBITS ECTOPIC MINERALIZATION BUT NOT BONE FORMATION
    Minamizaki, T.
    Toshishige, M.
    Yoshioka, H.
    Ahmed, F.
    Mine, Y.
    Yoshiko, Y.
    OSTEOPOROSIS INTERNATIONAL, 2019, 30 : S486 - S487
  • [4] Plasminogen activator inhibitor-1 from bone marrow-derived cells suppresses neointimal formation after vascular injury in mice
    Schaefer, Katrin
    Schroeter, Marco R.
    Dellas, Claudia
    Puls, Miriam
    Nitsche, Mirko
    Weiss, Elisabeth
    Hasenfuss, Gerd
    Konstantinides, Stavros V.
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2006, 26 (06) : 1254 - 1259
  • [5] Gut-derived Serotonin Is an Inhibitor of Bone Formation.
    Yadav, V. K.
    Ryu, J.
    Suda, N.
    Ducy, P.
    Karsenty, G.
    JOURNAL OF BONE AND MINERAL RESEARCH, 2008, 23 : S390 - S390
  • [6] Rabbit models provide insights into bone formation related biological process in atherosclerotic vascular calcification
    Tan, Linuo
    Wang, Zhen
    Li, Yixue
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 496 (04) : 1369 - 1375
  • [7] Nitric oxide inhibitor L-NAME suppresses mechanically induced bone formation in rats
    Turner, CH
    Takano, Y
    Owan, I
    Murrell, GAC
    AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 1996, 270 (04): : E634 - E639
  • [8] Over expression of bone sialoprotein enhances nodule formation and calcification in vascular smooth muscle cells.
    Harrington, S
    O'Brien, T
    Fitzpatrick, LA
    JOURNAL OF BONE AND MINERAL RESEARCH, 2001, 16 : S450 - S450
  • [9] The proteasome inhibitor, bortezomib suppresses primary myeloma and stimulates bone formation in myelomatous and nonmyelomatous bones in vivo
    Pennisi, Angela
    Li, Xin
    Ling, Wen
    Khan, Sharmin
    Zangari, Maurizio
    Yaccoby, Shmuel
    AMERICAN JOURNAL OF HEMATOLOGY, 2009, 84 (01) : 6 - 14
  • [10] A potent and orally active inhibitor of cathepsin K selectively suppresses bone resorption without affecting bone formation in cynomolgus monkeys
    Yamada, H
    Ochi, Y
    Kawada, N
    Nakanishi, Y
    Mori, H
    Kayasuga, R
    Hatayama, A
    Ohmoto, K
    Tanaka, M
    Kishikawa, K
    JOURNAL OF BONE AND MINERAL RESEARCH, 2005, 20 (09) : S253 - S253