The combination between NCSTN gene copy number variation and growth traits in Chinese cattle

被引:3
|
作者
Yao, Yu-Fei [1 ]
Lyu, Shijie [2 ]
Wang, Xianwei [3 ]
Zhang, Zijing [2 ]
Qu, Kaixing [4 ]
Xu, Jiawei [1 ]
Cai, Cuicui [5 ]
Li, Zhiming [3 ]
Xie, Jianliang [5 ]
Ru, Baorui [3 ]
Xu, Zejun [3 ]
Wang, Eryao [2 ]
Lei, Chuzhao [1 ]
Chen, Hong [1 ]
Huang, Bizhi [4 ]
Huang, Yongzhen [1 ]
机构
[1] Northwest A&F Univ, Coll Anim Sci & Technol, 22 Xinong Rd, Yangling 712100, Shaanxi, Peoples R China
[2] Henan Acad Agr Sci, Inst Anim Husb & Vet Sci, Zhengzhou, Henan, Peoples R China
[3] Henan Prov Anim Husb Gen Stn, Zhengzhou, Henan, Peoples R China
[4] Yunnan Acad Grassland & Anim Sci, Kunming 650212, Yunnan, Peoples R China
[5] Ningxia Acad Agr & Forestry Sci, Guyuan, Ningxia, Peoples R China
基金
中国国家自然科学基金;
关键词
NCSTN gene; copy number variation (CNV); Chinese cattle; growth traits; association analysis; EXPRESSION; GENOME;
D O I
10.1080/10495398.2020.1741382
中图分类号
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号
0905 ;
摘要
Copy number variation (CNV) has been used as an important source of phenotypic and genetic diversity in recent years. Nicastrin (NCSTN) gene is usually attached to human diseases such as Alzheimer's disease, and Acne inversa. However, there are no essays about the NCSTN gene combining with cattle breeds. In our study, we discovered different distributions of NCSTN gene copy number and associated it with phenotypic traits in four Chinese yellow cattle breeds (XN, PN, QC and YL). The result turned out that the CNV of the NCSTN gene was associated with several growth traits, such as cannon circumference, chest girth and rump length (p < 0.05). In general, we revealed the eminence over CNV of NCSTN gene and economic traits, suggesting that the CNV of the NCSTN gene can be considered to be a promising molecular breeding marker of Chinese beef cattle.
引用
收藏
页码:683 / 687
页数:5
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