Fluoride: A review of pre-clinical and clinical studies

被引：66

作者：

Sharma, Divya ^{[1
]}

Singh, Aarti ^{[2
]}

Verma, Kanika ^{[1
]}

Paliwal, Sarvesh ^{[1
]}

Sharma, Swapnil ^{[1
]}

Dwivedi, Jaya ^{[2
]}

机构：

[1] Banasthali Univ, Dept Pharm, Banasthali 304022, Rajasthan, India

[2] Banasthali Univ, Dept Chem, Banasthali, India

来源：

ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY | 2017年 / 56卷

关键词：

Fluoride; Toxicity; Beneficial effects; Pre-clinical; Clinical effects; ALUMINUM-INDUCED TOXICITY; TISSUE OXIDATIVE STRESS; SODIUM-FLUORIDE; DRINKING-WATER; REPRODUCTIVE-ORGANS; ADULT MICE; GASTROCNEMIUS-MUSCLE; TESTICULAR TOXICITY; LIPID-PEROXIDATION; SKELETAL FLUOROSIS;

D O I：

10.1016/j.etap.2017.10.008

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Fluoride is ubiquitous in environment and profound in bones, teeth and calcified tissues of human body. Fluoride has been the topic of regular discussion and investigations. Besides its toxicity, fluoride has also been examined for its beneficial effects like prevention and treatment of tooth decay, microbial infection, inflammation, cancer, occurrence of renal stone and many more. Since last many decades, several efforts have been made at pre-clinical and clinical level to understand role of fluoride in biological system. The present review gives a brief account of prevalence, sources of fluoride toxicity and pre-clinical and clinical studies carried out on effects of fluoride in last six decades.

引用

页码：297 / 313

页数：17

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