SUPERBUGS: THE POWERFUL WARRIORS

被引:5
|
作者
Kaur, Samanjit [1 ]
Hariharan, Sneha [2 ]
Dharmaraj, Selvakumar [2 ]
机构
[1] Mohamed Sathak Coll Art & Sci, Dept Biotechnol, Sholinganallur 600119, Tamil Nadu, India
[2] Karpagam Acad Higher Educ, FASH, Dept Biochem, Pollachi Main Rd, Coimbatore 641021, Tamil Nadu, India
关键词
Multidrug resistance; Antibiotics; Superbugs; METALLO-BETA-LACTAMASE; RESISTANCE;
D O I
10.13040/IJPSR.0975-8232.11(4).1506-26
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Antibiotics can no longer be considered as effective methods to treat various diseases. The misuse of these medicines has increased the evolvement of a number of drug-resistant microorganisms which are termed as "Superbugs". These are most prevalent in developing countries where the abuse of antibiotics is at the peak. Clostridium difficile, Streptococcus pneumoniae. MRSA (Staphylococcus aureus). ESBL (Escherichia colt) and NDM1-E. coli were some of the top listed superbugs. Different kinds of these superbugs attack many countries: even the United States of America. which is under danger from 14 types of superbugs and has lost less than 14,000 individuals every year form C. difficile alone. An NDM-1 strain bacterium. most dangerous superbug, produces a protein that can able to kill the movement of carbapenem antibiotics, which are used to treat a broad range of infections in Hospitals and health care centers. These superbugs can affect an individual by cold, fever. non-healing factors, and lead to organ failures. International and National Organizations should take serious initiatives to curb this problem and providing guidelines to prevent the spreading of these infections. This review details the importance of Superbugs and explains some of the preventative measures.
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页码:1506 / 1526
页数:21
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