Injectable, Biodegradable Hydrogels for Tissue Engineering Applications

被引：481
|
作者：
Tan, Huaping [1 ]
Marra, Kacey G. [1 ,2 ,3 ]
机构：
[1] Univ Pittsburgh, Dept Surg, Div Plast Surg, Pittsburgh, PA 15260 USA
[2] Univ Pittsburgh, Dept Bioengn, Pittsburgh, PA USA
[3] Univ Pittsburgh, McGowan Inst Regenerat Med, Pittsburgh, PA USA
来源：
MATERIALS | 2010年 / 3卷 / 03期
关键词：
injectable hydrogels; biodegradation; biomaterials; tissue engineering; regeneration medicine; IN-VITRO EVALUATION; FIBROBLAST-GROWTH-FACTOR; POLY(ETHYLENE GLYCOL) HYDROGELS; POLY(VINYL ALCOHOL) HYDROGELS; MESENCHYMAL STEM-CELLS; LINKING AGENT GENIPIN; ACID-BASED HYDROGELS; HYALURONIC-ACID; CROSS-LINKING; CHONDROGENIC DIFFERENTIATION;
D O I：
10.3390/ma3031746
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
Hydrogels have many different applications in the field of regenerative medicine. Biodegradable, injectable hydrogels could be utilized as delivery systems, cell carriers, and scaffolds for tissue engineering. Injectable hydrogels are an appealing scaffold because they are structurally similar to the extracellular matrix of many tissues, can often be processed under relatively mild conditions, and may be delivered in a minimally invasive manner. This review will discuss recent advances in the field of injectable hydrogels, including both synthetic and native polymeric materials, which can be potentially used in cartilage and soft tissue engineering applications.
引用
收藏
页码：1746 / 1767
页数：22
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