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The safety and efficacy of salicylic acid chemical peels in darker racial-ethnic groups
被引:166
|作者:
Grimes, PE
机构:
[1] Vitiglio & Pigmentat Inst So Calif, Los Angeles, CA USA
[2] Univ Calif Los Angeles, Div Dermatol, Los Angeles, CA 90024 USA
关键词:
D O I:
10.1046/j.1524-4725.1999.08145.x
中图分类号:
R75 [皮肤病学与性病学];
学科分类号:
100206 ;
摘要:
BACKGROUND. There is a dearth of published data regarding chemical peels in darker racial-ethnic groups. OBJECTIVE. The purpose of the present investigation was to assess the clinical efficacy and safety of a new superficial salicylic acid peel in individuals of skin types V and VI. METHODS. Twenty-five patients were included in this pilot investigation. Nine had acne vulgaris, 5 had post-inflammatory hyperpigmentation, 6 had melasma, and 5 had rough, oily skin with enlarged pores. The patients were pre-treated for 2 weeks with hydroquinone 4% prior to undergoing a series of five salicylic acid chemical peels. The concentrations of salicylic acid were 20% and 30%. The peels were performed at 2 week intervals. RESULTS. Moderate to significant improvement was observed in 88% of the patients. Minimal to mild side effects occurred in 16%. CONCLUSION. The results of this study suggest that superficial salicylic acid peels are both safe and efficacious for treatment of acne vulgaris, oily skin, textural changes, melasma, and post-inflammatory hyperpigmentation in patients with skin types V and VI.
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页码:18 / 22
页数:5
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