Alopecia Areata. Current situation and perspectives

被引:0
|
作者
Juarez-Rendon, Karina J. [1 ]
Rivera Sanchez, Gildardo [1 ]
Reyes-Lopez, Miguel A. [1 ]
Garcia-Ortiz, Jose E. [2 ]
Bocanegra-Garcia, Virgilio [1 ]
Guardiola-Avila, Iliana [1 ]
Altamirano-Garcia, Maria L. [3 ]
机构
[1] Inst Politecn Nacl Reynosa, Ctr Biotecnol Genom, Tamaulipas, Mexico
[2] Inst Mexicano Seguro Social, Ctr Med Nacl Occidente, Ctr Invest Biomed Occidente, Div Genet, Guadalajara, Jalisco, Mexico
[3] Ctr Dermatol Brunnenhalt Reynosa Reynosa, Tamaulipas, Mexico
来源
ARCHIVOS ARGENTINOS DE PEDIATRIA | 2017年 / 115卷 / 06期
关键词
Alopecia Areata; genes; susceptibility; SINGLE-NUCLEOTIDE POLYMORPHISMS; GENE POLYMORPHISMS; KOREAN POPULATION; FUNCTIONAL POLYMORPHISMS; CORTICOSTEROID-THERAPY; ASSOCIATION ANALYSIS; TURKISH POPULATION; CHINESE POPULATION; PROMOTER REGIONS; RISK;
D O I
10.5546/aap.2017.eng.e404
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Alopecia areata (AA) is a dermatological disease characterized by non-scarring hair loss of the scalp and/or body, with an unpredictable and variable evolution in the patients in which, despite multidisciplinary efforts, its etiology is not entirely known, although some evidence suggests that environmental, immunological and genetic factors could be generating the disease. The aim of this review is to provide an updated panorama of the clinical characteristics, diagnosis and treatment of AA, to analyze the mechanisms that could participate in its etiology, as well as to review some of the most important genetic variants that could confer susceptibility to the development of this disease.
引用
收藏
页码:E404 / E411
页数:8
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