Non-Invasive Measurement of Human Blood Cholesterol Concentration Based on Dynamic Spectrum Method

被引：4

作者：

Suo Yong-kuan ^{[1
,2
]}

Li Gang ^{[2
]}

Wang Hui-quan ^{[2
]}

Lin Ling ^{[2
]}

机构：

[1] China Med Univ, Shenyang 110001, Peoples R China

[2] Tianjin Univ, State Key Lab Precis Measuring Technol & Instrume, Tianjin 300072, Peoples R China

来源：

SPECTROSCOPY AND SPECTRAL ANALYSIS | 2012年 / 32卷 / 01期

关键词：

Total cholesterol; Dynamic spectra; Principle component analysis(PCA); Artificial neural network;

D O I：

10.3964/j.issn.1000-0593(2012)01-0188-04

中图分类号：

O433 [光谱学];

学科分类号：

0703 ; 070302 ;

摘要：

For non-invasive measurement of human blood cholesterol concentration, this experiment was carried out on 80 volunteers clinically. In vivo dynamic spectra of fingers were achieved and biochemical examinations of blood components contents including cholesterol were get as soon as possible. BP artificial neural network with inputs of dynamic spectra plus energy of harmonic waves processed by Principal Components Analysis(PCA) was used to establish the model of the total cholesterol values. The correlation between the predicted value and the true value of cholesterol is 96. 48%. The maximum relative error is 25. 44% and root-mean-square error of prediction is 0. 242 6 mmol . L-1. The results show that PCA can make the process of computing faster and this study is another advance of dynamic spectra.

引用

页码：188 / 191

页数：4

共 14 条

[1] Principal component analysis of spectral perturbation parameters for voice pathology detection
Gómez, P
Díaz, F
Alvarez, A
Murphy, K
Lázaro, C
Martínez, R
Rodellar, V
[J]. 18th IEEE Symposium on Computer-Based Medical Systems, Proceedings, 2005, : 41 - 46
[2] Lan Xiu-feng, 2008, Acta Photonica Sinica, V37, P547
[3] Li G, 2004, PROCEEDINGS OF THE THIRD INTERNATIONAL SYMPOSIUM ON INSTRUMENTATION SCIENCE AND TECHNOLOGY, VOL 3, P875
[4] Li G, 2006, J INFRARED MILLIM W, V25, P345
[5] [李刚 Li Gang], 2011, [天津大学学报, Journal of Tianjin University], V44, P90
[6] LIU R, 2008, J TIANJIN U, V41
[7] [罗云瀚 LUO Yunhan], 2008, [激光与红外, Laser and Infrared], V38, P465
[8] Non-invasive glucose measurements in mice using mid-infrared emission spectroscopy
Mueller, Marcel
Grunze, Michael
Leiter, Edward H.
Reifsnyder, Peter C.
Klueh, Ulrike
Kreutzer, Don
[J]. SENSORS AND ACTUATORS B-CHEMICAL, 2009, 142 (02) : 502 - 508
[9] Near-infrared spectroscopy: A methodology-focused review
Pellicer, Adelina
del Carmen Bravo, Maria
[J]. SEMINARS IN FETAL & NEONATAL MEDICINE, 2011, 16 (01): : 42 - 49
[10] Non-invasive prediction of hematocrit levels by portable visible and near-infrared spectrophotometer
Sakudo, Akikazu
Kato, Yukiko Hakariya
Kuratsune, Hirohiko
Ikuta, Kazuyoshi
[J]. CLINICA CHIMICA ACTA, 2009, 408 (1-2) : 123 - 127

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