Syringomyelia in patient with neuromyelitis optica spectrum disorder: a case report

Neuromyelitis optica spectrum disorder (NMOSD) is an idiopathic inflammatory demyelinating disease characterized by longitudinally extensive transverse myelitis (LETM) and optic neuritis. This article reported a case of a 58-year-old women initially presented with asymmetric tetraparesis and binocular vision diminution. MRI (full name please) showed the longitudinal syringomyelia from C3 to T1 vertebral segments. Combined with the clinical manifestations and laboratory examinations especially seropositivity of NMO-IgG, the patient was ultimately diagnosed as NMOSD. This case report suggested that radiological findings of syringomyelia should be considered the possibility of NMOSD, especially in patients with a history of typical myelitis symptoms and seropositivity of NMO-IgG.