Vitamin D regulation of cathelicidin in the skin: Toward a renaissance of vitamin D in dermatology?

被引：26
|
作者：
Segaert, Siegfried [1 ]
机构：
[1] Univ Hosp Leuven, Dept Dermatol, Louvain, Belgium
来源：
JOURNAL OF INVESTIGATIVE DERMATOLOGY | 2008年 / 128卷 / 04期
关键词：
D O I：
10.1038/jid.2008.35
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
1,25- Dihydroxyvitamin D-3, the active form of vitamin D, is a major regulator of the expression of the cationic antimicrobial peptide cathelicidin, not only in monocytes but also in epidermal keratinocytes. The involvement of cathelicidin in wound healing and skin diseases as diverse as psoriasis, rosacea, and atopic dermatitis may create new opportunities for the use of vitamin D in dermatology.
引用
收藏
页码：773 / 775
页数：4
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