Enhanced Transduction of Human Hematopoietic Stem Cells by AAV6 Vectors: Implications in Gene Therapy and Genome Editing

被引：0
|
作者：
Yang, Hua [1 ]
Qing, Keyun [1 ]
Keeler, Geoffrey D. [1 ]
Yin, Ling [1 ]
Mietzsch, Mario [2 ]
Ling, Chen [3 ]
Hoffman, Brad E. [1 ]
Agbandje-McKenna, Mavis [2 ]
Tan, Mengqun [4 ]
Wang, Wei [5 ]
Srivastava, Arun [1 ]
机构：
[1] Univ Florida, Pediat, Gainesville, FL USA
[2] Univ Florida, Biochem & Mol Biol, Gainesville, FL USA
[3] Fudan Univ, Genet Engn, Shanghai, Peoples R China
[4] Cent South Univ, Physiol, Changsha, Peoples R China
[5] Cent South Univ, Inst Cell & Gene Therapy, Changsha, Peoples R China
来源：
MOLECULAR THERAPY | 2020年 / 28卷 / 04期
关键词：
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
559
引用
收藏
页码：248 / 248
页数：1
相关论文
共 50 条
  • [1] Enhanced Transduction of Human Hematopoietic Stem Cells by AAV6 Vectors: Implications in Gene Therapy and Genome Editing
    Yang, Hua
    Qing, Keyun
    Keeler, Geoffrey D.
    Yin, Ling
    Mietzsch, Mario
    Ling, Chen
    Hoffman, Brad E.
    Agbandje-McKenna, Mavis
    Tan, Mengqun
    Wang, Wei
    Srivastava, Arun
    MOLECULAR THERAPY-NUCLEIC ACIDS, 2020, 20 : 451 - 458
  • [2] Mechanism of Transduction of Human Hematopoietic Cells by Recombinant AAV6 Vectors
    Song, Liujiang
    Li, Baozheng
    Wang, Yuan
    Ma, Wenqin
    Aslanidi, George V.
    Ling, Chen
    Ling, Changquang
    Tan, Mengqun
    Srivastava, Arun
    MOLECULAR THERAPY, 2012, 20 : S229 - S230
  • [3] High-Efficiency Transduction of Primary Human Hematopoietic Stem/Progenitor Cells by AAV6 Vectors: Strategies for Overcoming Donor-Variation and Implications in Genome Editing
    Ling, Chen
    Bhukhai, Kanit
    Yin, Zifei
    Tan, Mengqun
    Yoder, Mervin C.
    Leboulch, Philippe
    Payen, Emmanuel
    Srivastava, Arun
    SCIENTIFIC REPORTS, 2016, 6
  • [4] High-Efficiency Transduction of Primary Human Hematopoietic Stem/Progenitor Cells By AAV6 Vectors: strategies for Overcoming Donor-Variation and Implications in Genome Editing
    Ling, Chen
    Bhukhai, Kanit
    Yin, Zifei
    Tan, Mengqun
    Yoder, Mervin
    Leboulch, Philippe
    Payen, Emmanuel
    Srivastava, Arun
    BLOOD, 2016, 128 (22)
  • [5] High-Efficiency Transduction of Primary Human Hematopoietic Stem/Progenitor Cells by AAV6 Vectors: Strategies for Overcoming Donor-Variation and Implications in Genome Editing
    Chen Ling
    Kanit Bhukhai
    Zifei Yin
    Mengqun Tan
    Mervin C. Yoder
    Philippe Leboulch
    Emmanuel Payen
    Arun Srivastava
    Scientific Reports, 6
  • [6] High-Efficiency Transduction of Primary Human CD34+ Hematopoietic Stem/Progenitor Cells by AAV6 Serotype Vectors: Strategies for Overcoming Donor Variation and Implications in Genome Editing
    Yin, Zifei
    Bukhai, Kanit
    Aslanidi, George
    Ling, Chen
    Tan, Mengqun
    Yoder, Mervin
    Leboulch, Philippe
    Payen, Emmanuel
    Srivastava, Arun
    MOLECULAR THERAPY, 2016, 24 : S5 - S6
  • [7] Optimizing AAV6 Transduction of Lymphocytes to Increase Targeted Genome Editing
    Rogers, Geoffrey L.
    Amora, Rainier
    Huang, Chun
    Chen, Hsu-Yu
    Seclen, Eduardo
    Holmes, Michael C.
    Riley, Brigit E.
    Cannon, Paula M.
    MOLECULAR THERAPY, 2018, 26 (05) : 366 - 366
  • [8] Homology-driven genome editing in hematopoietic stem and progenitor cells using ZFN mRNA and AAV6 donors
    Jianbin Wang
    Colin M Exline
    Joshua J DeClercq
    G Nicholas Llewellyn
    Samuel B Hayward
    Patrick Wai-Lun Li
    David A Shivak
    Richard T Surosky
    Philip D Gregory
    Michael C Holmes
    Paula M Cannon
    Nature Biotechnology, 2015, 33 : 1256 - 1263
  • [9] Homology-driven genome editing in hematopoietic stem and progenitor cells using ZFN mRNA and AAV6 donors
    Wang, Jianbin
    Exline, Colin M.
    DeClercq, Joshua J.
    Llewellyn, G. Nicholas
    Hayward, Samuel B.
    Li, Patrick Wai-Lun
    Shivak, David A.
    Surosky, Richard T.
    Gregory, Philip D.
    Holmes, Michael C.
    Cannon, Paula M.
    NATURE BIOTECHNOLOGY, 2015, 33 (12) : 1256 - +
  • [10] Optimization of AAV6 transduction enhances site-specific genome editing of primary human lymphocytes
    Rogers, Geoffrey L.
    Huang, Chun
    Clark, Robert D. E.
    Seclen, Eduardo
    Chen, Hsu-Yu
    Cannon, Paula M.
    MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, 2021, 23 : 198 - 209
12345