Combined EEG-fMRI and tractography to visualise propagation of epileptic activity

被引:52
|
作者
Hamandi, K. [1 ]
Powell, H. W. R. [1 ]
Laufs, H. [1 ]
Symms, M. R. [1 ]
Barker, G. J. [2 ]
Parker, G. J. M. [3 ]
Lemieux, L. [1 ]
Duncan, J. S. [1 ]
机构
[1] UCL, Dept Clin & Expt Epilepsy, Inst Neurol, London, England
[2] Kings Coll London, Inst Psychiat, London WC2R 2LS, England
[3] Univ Manchester, Imaging Sci & Biomed Engn, Manchester, Lancs, England
来源
基金
英国医学研究理事会; 英国惠康基金;
关键词
D O I
10.1136/jnnp.2007.125401
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
In a patient with refractory temporal lobe epilepsy, EEG-fMRI showed activation in association with left anterior temporal interictal discharges, in the left temporal, parietal and occipital lobes. Dynamic causal modelling suggested propagation of neural activity from the temporal focus to the area of occipital activation. Tractography showed connections from the site of temporal lobe activation to the site of occipital activation. This demonstrates the principle of combining EEG-fMRI and tractography to delineate the pathways of propagation of epileptic activity.
引用
收藏
页码:594 / 597
页数:4
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