Compartmentalized microfluidic lung epithelial cell culture device for pulmonary mechanotransduction studies

被引：0

作者：

Huh, D ^{[1
]}

Kamotani, Y ^{[1
]}

Grotberg, JB ^{[1
]}

Takayama, S ^{[1
]}

机构：

[1] Univ Michigan, Dept Biomed Engn, Ann Arbor, MI 48109 USA

来源：

Micro Total Analysis Systems 2004, Vol 2 | 2005年 / 297期

关键词：

lung epithelial cell; microfluidic cell culture; mechanical stress; flow;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Pulmonary epithelial cells are exposed to various fluid flows during breathing or mechanical ventilation. Mechanical stresses generated by the movement of fluids affect function and phenotype of lung cells, and sometimes mediate the development of pulmonary diseases. This paper describes a compartmentalized microfluidic lung epithelial cell culture device that mimics in vivo microenvironment with different flows under normal and pathological pulmonary conditions.

引用

页码：282 / 284

页数：3

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