Aging alters visual processing of objects and shapes in inferotemporal cortex in monkeys

被引：3
|
作者：
Csete, G. [1 ,2 ]
Bognar, A. [1 ]
Csibri, P. [1 ]
Kaposvari, P. [1 ]
Sary, Gy. [1 ]
机构：
[1] Univ Szeged, Fac Med, Dept Physiol, H-6720 Szeged, Hungary
[2] Fac Med, Dept Neurol, H-6725 Szeged, Hungary
来源：
BRAIN RESEARCH BULLETIN | 2015年 / 110卷
关键词：
Perceptual deficit; Aging; Shape vision; Inferotemporal cortex; Monkey; AGE-RELATED-CHANGES; FRONTAL EYE FIELD; FUNCTIONAL DEGRADATION; NEURAL ACTIVITY; CORTICAL-CELLS; LIFE-SPAN; MACAQUE; NEURONS; RESPONSES; PATTERN;
D O I：
10.1016/j.brainresbull.2014.11.005
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Visual perception declines with age. Perceptual deficits may originate not only in the optical system serving vision but also in the neural machinery processing visual information. Since homologies between monkey and human vision permit extrapolation from monkeys to humans, data from young, middle aged and old monkeys were analyzed to show age-related changes in the neuronal activity in the inferotemporal cortex, which is critical for object and shape vision. We found an increased neuronal response latency, and a decrease in the stimulus selectivity in the older animals and suggest that these changes may underlie the perceptual uncertainties found frequently in the elderly. (C) 2014 Elsevier Inc. All rights reserved.
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页码：76 / 83
页数：8
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