Entrepreneurship education in environmental science specialty lagged behind need for China, therefore it is imperative for it to enhance entrepreneurship education reform in environmental science. Entrepreneurship education is an important content of environmental science specialty in local undergraduate university. Entrepreneurship education reform in environmental science was carried out in Wenzhou University. The reform proposed education reform problems and ideas in environmental science, but also put forward six entrepreneurship models of environmental science specialty such as the environmental information services company, ecotourism company, environmental training institutions, energy-saving technology services company, environmental engineering design company and environmental creative services company. According to their character and ability, college students may select different entrepreneurship modes, and focused on related technical and entrepreneurial knowledge. The enthusiasm and talent of college students were improved through the reform, and which achieved good results.