Therapeutic Hypothermia for Perinatal Asphyxia in India-Experience and Evidence

被引：4
|
作者：
Umamaheswari, B. [1 ]
Amboiram, Prakash [1 ]
Adhisivam, B. [2 ]
Bhat, B. Vishnu [3 ]
机构：
[1] Sri Ramachandra Inst Higher Educ & Res, Dept Neonatol, Chennai, Tamil Nadu, India
[2] Jawaharlal Inst Postgrad Med Educ & Res JIPMER, Dept Neonatol, Pondicherry, India
[3] Aarupadai Veedu Med Coll & Hosp, Dept Pediat & Neonatol, Vinayaka Miss Res Fdn DU, Pondicherry 609602, India
来源：
INDIAN JOURNAL OF PEDIATRICS | 2022年 / 89卷 / 08期
关键词：
Neonate; Hypoxic-ischemic encephalopathy; Therapeutic hypothermia; Neonatal mortality; Neurodevelopment; HYPOXIC-ISCHEMIC ENCEPHALOPATHY; PHASE CHANGING MATERIAL; WHOLE-BODY HYPOTHERMIA; BRAIN-INJURY; TERM; METABOLISM; BIOMARKERS; INFANTS; BABIES;
D O I：
10.1007/s12098-022-04187-z
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
Therapeutic hypothermia is an established therapy with proven benefit for term neonates with moderate and severe hypoxic-ischemic encephalopathy (HIE). Many centers in India have started therapeutic cooling of asphyxiated infants. There is enough evidence for the beneficial effect of cooling from the randomized trials conducted in India. However, the recently published hypothermia for encephalopathy in low- and middle-income countries (HELIX) trial has contrasting findings. In this context, this review is written summarizing the available experience and evidence for therapeutic hypothermia for perinatal asphyxia in India.
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收藏
页码：804 / 811
页数：8
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