Pancreatic cancer: Current research and future directions

被引：85

作者：

Falasca, Marco ^{[1
]}

Kim, Minkyoung ^{[1
]}

Casari, Ilaria ^{[1
]}

机构：

[1] Curtin Univ, CHIRI Biosci, Sch Biomed Sci, Metab Signalling Grp, Perth, WA 6845, Australia

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER | 2016年 / 1865卷 / 02期

关键词：

Pancreatic cancer; Cancer metabolism; Tumour stroma; MicroRNA; Exosomes; TUMOR-SUPPRESSOR GENE; MESENCHYMAL TRANSITION; STROMAL BIOLOGY; STEM-CELLS; EXOSOMES; AUTOPHAGY; KRAS; METABOLISM; INHIBITION; CHEMOTHERAPY;

D O I：

10.1016/j.bbcan.2016.01.001

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Despite the survival rate advancements in different types of cancer in the last 40 years, the perspective for pancreatic cancer patients has seen no substantial changes. Indeed, the five year survival rate remains around 5%. Nevertheless, in the last decade we have witnessed an increased interest in pancreatic cancer biology and this has produced a substantial increment in our knowledge on pancreatic cancer progression. The big challenge is now to translate this knowledge in better outcomes for patients. The aim of this review is to describe the latest discoveries and advancements in pancreatic cancer research and to discuss future directions. (C) 2016 Elsevier B.V. All rights reserved.

引用

页码：123 / 132

页数：10

共 50 条

[1] Pancreatic cancer: current standards, research updates and future directions
Hsueh, Chung-Tsen
[J]. JOURNAL OF GASTROINTESTINAL ONCOLOGY, 2011, 2 (03) : 123 - 125
[2] Oncolytic viral therapy for pancreatic cancer: current research and future directions
Ady, Justin W.
Heffner, Jacqueline
Klein, Elizabeth
Fong, Yuman
[J]. ONCOLYTIC VIROTHERAPY, 2014, 3 : 35 - 46
[3] Microorganisms in chemotherapy for pancreatic cancer: An overview of current research and future directions
Lu, Si-Yuan
Hua, Jie
Xu, Jin
Wei, Miao-Yan
Liang, Chen
Meng, Qing-Cai
Liu, Jiang
Zhang, Bo
Wang, Wei
Yu, Xian-Jun
Shi, Si
[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2021, 17 (10): : 2666 - 2682
[4] Genomics meets immunity in pancreatic cancer: Current research and future directions for pancreatic adenocarcinoma immunotherapy
Bowers, Jacob S.
Bailey, Stefanie R.
Rubinstein, Mark P.
Paulos, Chrystal M.
Camp, E. Ramsay
[J]. ONCOLOGY REVIEWS, 2019, 13 (02): : 102 - 113
[5] Current treatment and future directions for advanced pancreatic cancer
Rothenberg, ML
[J]. PANCREATIC CANCER: ADVANCES IN MOLECULAR PATHOLOGY, DIAGNOSIS & CLINICAL MANAGEMENT, 1998, : 157 - 164
[6] The Current Role of Radiation in Pancreatic Cancer and Future Directions
Hill, Colin S.
Herman, Joseph M.
[J]. CLINICAL COLORECTAL CANCER, 2023, 22 (01) : 12 - 23
[7] Immunotherapy in Pancreatic Cancer: Current Status and Future Directions
Zhang, Jubao
[J]. JOURNAL OF THE PANCREAS, 2024, 25 (03): : 7 - 8
[8] Management of pancreatic cancer: Current status and future directions
H. Ramesh
[J]. Indian Journal of Surgery, 2009, 71 : 368 - 372
[9] Management of Pancreatic Cancer: Current Status and Future Directions
Ramesh, H.
[J]. INDIAN JOURNAL OF SURGERY, 2010, 72 (04) : 285 - 289
[10] Current Status and Future Directions in the Management of Pancreatic Cancer
Chandrakanth Are
Asish Patel
[J]. Indian Journal of Surgical Oncology, 2015, 6 (1) : 3 - 5

← 1 2 3 4 5 →