Synthesis of C-3 alkyl analogs of cocaine

被引：5
|
作者：
Deng, SM [1 ]
Huang, DW [1 ]
Landry, DW [1 ]
机构：
[1] Columbia Univ, Dept Med, Div Clin Pharmacol & Expt Therapeut, New York, NY 10032 USA
来源：
TETRAHEDRON LETTERS | 2001年 / 42卷 / 36期
关键词：
D O I：
10.1016/S0040-4039(01)01254-0
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The first general stereocontrolled approach to C-3 alkyl analogs of cocaine is described. The route utilized versatile intermediates 2 beta -hydroxymethyl-3 alpha -cyanotropane and 2 beta -hydroxymethyl-3 beta -cyanotropane. (C) 2001 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：6259 / 6261
页数：3
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